Copper- and Palladium-Catalyzed Cross-Coupling Reactions for the Synthesis of N-Fused Benzo[4,5]imidazo[2,1-b]thiazole Derivatives via Substituted trans-1,2-Diiodoalkenes, 1H-Benzo[d]imidazole-2-thiols, and Halobenzenes

被引：34

作者：

Shen, Guodong ^{[1
]}

Yang, Bingchuan ^{[1
]}

Huang, Xianqiang ^{[1
]}

Hou, Yaxin ^{[1
]}

Gao, Huan ^{[1
]}

Cui, Jichun ^{[1
]}

Cui, Chuansheng ^{[1
]}

Zhang, Tongxin ^{[1
]}

机构：

[1] Liaocheng Univ, Sch Chem & Chem Engn, Sch Pharm, Liaocheng 252000, Shandong, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 07期

基金：

中国国家自然科学基金;

关键词：

BOND FORMATION; C-C; ARYLATION; HETEROCYCLES; INHIBITOR; AGENTS; ATOM;

D O I：

10.1021/acs.joc.7b00162

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two transition metal (Cu and Pd)-catalyzed C.-S, C-N, and C-C bond cross-coupling reactions for the preparation of N-fused benzo [4,5]imidazo [2,1-b]thiazole derivatives were developed. A variety of 3-substituted and 2,3-disubstituted benzo[4,5]iinidazo[2,1-b]thiazoles were efficiently and conveniently synthesized from the coupling reaction-via trans-1,2-diiodoalkenes, 1H-benzo[d]imidazole-2thiols, and halobenzenes in moderate to excellent yields.

引用

页码：3798 / 3805

页数：8

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