Chromatography-free synthesis of 1,2,4-oxadiazoles using ROMPGEL-supported acylating reagents

被引：22
作者：
Barrett, AGM [1 ]
Cramp, SM
Roberts, RS
Zécri, FJ
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England
[2] Aventis CorpSci, Ongar CM5 0HW, Essex, England
来源：
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING | 2000年 / 3卷 / 02期
关键词：
D O I：
10.2174/1386207003331733
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
1,2,4-Oxadiazoles were synthesized in solution from aromatic amidoximes and acylating agents supported on a ring opening metathesis polymer (ROMPGEL) backbone. High yields and purities of the 1,2,4-oxadiazoles were obtained with minimal purification.
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页码：131 / 138
页数：8
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