共 30 条
Chromatography-free synthesis of 1,2,4-oxadiazoles using ROMPGEL-supported acylating reagents
被引:22
作者:

Barrett, AGM
论文数: 0 引用数: 0
h-index: 0
机构:
Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England

Cramp, SM
论文数: 0 引用数: 0
h-index: 0
机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England

Roberts, RS
论文数: 0 引用数: 0
h-index: 0
机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England

Zécri, FJ
论文数: 0 引用数: 0
h-index: 0
机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England
机构:
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England
[2] Aventis CorpSci, Ongar CM5 0HW, Essex, England
关键词:
D O I:
10.2174/1386207003331733
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
1,2,4-Oxadiazoles were synthesized in solution from aromatic amidoximes and acylating agents supported on a ring opening metathesis polymer (ROMPGEL) backbone. High yields and purities of the 1,2,4-oxadiazoles were obtained with minimal purification.
引用
收藏
页码:131 / 138
页数:8
相关论文
共 30 条
- [1] A ROMPGEL-supported N-hydroxysuccinimide:: A host of acylations with minimal purification[J]. ORGANIC LETTERS, 2000, 2 (03) : 261 - 264Barrett, AGM论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandCramp, SM论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandRoberts, RS论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandZecri, FJ论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England
- [2] Horner-Emmons synthesis with minimal purification using ROMPGEL: A novel high-loading matrix for supported reagents[J]. ORGANIC LETTERS, 1999, 1 (04) : 579 - 582Barrett, AGM论文数: 0 引用数: 0 h-index: 0机构: Univ London Sch Pharm, Dept Chem, London SW7 2AY, England Univ London Sch Pharm, Dept Chem, London SW7 2AY, EnglandCramp, SM论文数: 0 引用数: 0 h-index: 0机构: Univ London Sch Pharm, Dept Chem, London SW7 2AY, EnglandRoberts, RS论文数: 0 引用数: 0 h-index: 0机构: Univ London Sch Pharm, Dept Chem, London SW7 2AY, EnglandZecri, FJ论文数: 0 引用数: 0 h-index: 0机构: Univ London Sch Pharm, Dept Chem, London SW7 2AY, England
- [3] ROMP-spheres: A novel high-loading polymer support using cross metathesis between vinyl polystyrene and norbornene derivatives[J]. ORGANIC LETTERS, 1999, 1 (07) : 1083 - 1086Barrett, AGM论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandCramp, SM论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandRoberts, RS论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England
- [4] Rapid entry into mono-, bi-, and tricyclic β-lactam arrays via alkene metathesis[J]. JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (22) : 7893 - 7907Barrett, AGM论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandBaugh, SPD论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandBraddock, DC论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandFlack, K论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandGibson, VC论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandGiles, MR论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandMarshall, EL论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandProcopiou, PA论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandWhite, AJP论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, EnglandWilliams, DJ论文数: 0 引用数: 0 h-index: 0机构: Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England
- [5] SYNTHESIS OF STAR BLOCK COPOLYMERS BY CONTROLLED RING-OPENING METATHESIS POLYMERIZATION[J]. MACROMOLECULES, 1991, 24 (04) : 817 - 823BAZAN, GC论文数: 0 引用数: 0 h-index: 0机构: MIT,DEPT CHEM,6-331,CAMBRIDGE,MA 02139 MIT,DEPT CHEM,6-331,CAMBRIDGE,MA 02139SCHROCK, RR论文数: 0 引用数: 0 h-index: 0机构: MIT,DEPT CHEM,6-331,CAMBRIDGE,MA 02139 MIT,DEPT CHEM,6-331,CAMBRIDGE,MA 02139
- [6] Solid-supported reagent strategies for rapid purification of combinatorial synthesis products[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1999, 32 (01) : 18 - 26Booth, RJ论文数: 0 引用数: 0 h-index: 0机构: Warner Lambert Parke Davis, Pharmaceut Res, Ann Arbor, MI 48105 USA Warner Lambert Parke Davis, Pharmaceut Res, Ann Arbor, MI 48105 USAHodges, JC论文数: 0 引用数: 0 h-index: 0机构: Warner Lambert Parke Davis, Pharmaceut Res, Ann Arbor, MI 48105 USA Warner Lambert Parke Davis, Pharmaceut Res, Ann Arbor, MI 48105 USA
- [7] Access to well-defined heterogeneous catalytic systems via ring-opening metathesis polymerization (ROMP): Applications in palladium(II)-mediated coupling reactions[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (48) : 11101 - 11107Buchmeiser, MR论文数: 0 引用数: 0 h-index: 0机构: Univ Innsbruck, Inst Analyt Chem & Radiochem, A-6020 Innsbruck, Austria Univ Innsbruck, Inst Analyt Chem & Radiochem, A-6020 Innsbruck, AustriaWurst, K论文数: 0 引用数: 0 h-index: 0机构: Univ Innsbruck, Inst Analyt Chem & Radiochem, A-6020 Innsbruck, Austria
- [8] Ring-opening-metathesis polymerization for the preparation of carboxylic-acid-functionalized, high-capacity polymers for use in separation techniques[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (39) : 9166 - 9174Buchmeiser, MR论文数: 0 引用数: 0 h-index: 0机构: Inst. Analyt. Chem. and Radiochem., University of Innsbruck Innrain 52aAtzl, N论文数: 0 引用数: 0 h-index: 0机构: Inst. Analyt. Chem. and Radiochem., University of Innsbruck Innrain 52aBonn, GK论文数: 0 引用数: 0 h-index: 0机构: Inst. Analyt. Chem. and Radiochem., University of Innsbruck Innrain 52a
- [9] IMPROVED FISCHER INDOLE REACTION FOR THE PREPARATION OF N,N-DIMETHYLTRYPTAMINES - SYNTHESIS OF L-695,894, A POTENT 5-HT1D RECEPTOR AGONIST[J]. JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (13) : 3738 - 3741CHEN, CY论文数: 0 引用数: 0 h-index: 0机构: Department of Process Research, Merck Research Laboratories, Division of Merck & Co., Inc., Rahway, New Jersey 07065SENANAYAKE, CH论文数: 0 引用数: 0 h-index: 0机构: Department of Process Research, Merck Research Laboratories, Division of Merck & Co., Inc., Rahway, New Jersey 07065BILL, TJ论文数: 0 引用数: 0 h-index: 0机构: Department of Process Research, Merck Research Laboratories, Division of Merck & Co., Inc., Rahway, New Jersey 07065LARSEN, RD论文数: 0 引用数: 0 h-index: 0机构: Department of Process Research, Merck Research Laboratories, Division of Merck & Co., Inc., Rahway, New Jersey 07065VERHOEVEN, TR论文数: 0 引用数: 0 h-index: 0机构: Department of Process Research, Merck Research Laboratories, Division of Merck & Co., Inc., Rahway, New Jersey 07065REIDER, PJ论文数: 0 引用数: 0 h-index: 0机构: Department of Process Research, Merck Research Laboratories, Division of Merck & Co., Inc., Rahway, New Jersey 07065
- [10] A SIMPLIFIED PROCEDURE FOR PREPARING 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLES BY REACTION OF AMIDOXIMES WITH ACYL CHLORIDES IN PYRIDINE SOLUTION[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1989, 26 (01) : 125 - 128CHIOU, S论文数: 0 引用数: 0 h-index: 0SHINE, HJ论文数: 0 引用数: 0 h-index: 0