Biocatalytic reactions in hydrophobic ionic liquids

被引:112
作者
Sureshkumar, Manthiriyappan [1 ]
Lee, Cheng-Kang [1 ]
机构
[1] Natl Taiwan Univ Sci & Technol, Dept Chem Engn, Biomol Engn Lab, Taipei 106, Taiwan
关键词
Biologically active compounds; Volatile organic compounds (VOCs); Hydrophobic ionic liquids (ILs); 1-Butyl-3-methylimidazolium hexafluorophosphate ([Bmim] PF6); Supercritical carbon dioxide (scCO(2)); LIPASE-CATALYZED TRANSESTERIFICATION; SUPERCRITICAL CARBON-DIOXIDE; CANDIDA-RUGOSA LIPASE; DYNAMIC KINETIC RESOLUTION; PRESSURE PHASE-BEHAVIOR; ACID ESTER SYNTHESIS; ORGANIC-SOLVENTS; ENHANCED ENANTIOSELECTIVITY; ENZYMATIC CATALYSIS; ALPHA-CHYMOTRYPSIN;
D O I
10.1016/j.molcatb.2009.03.008
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Medium engineering for biocatalytic reactions is imperative approach for the synthesis of biologically active compounds. Biocatalytic reaction media holding water, organic solvent and supercritical fluids have become well established for commercial applications. Non-aqueous biocatalytic reactions carry significant advantages that non-polar substrate can be specifically reacted and/or product recovered efficiently. On the other hand, usage of conventional organic solvents as non-aqueous medium affects green chemistry aspects. Hydrophobic ionic liquids (ILs) provide desirable environment for many enzymatic reactions as conventional organic solvents do but without emission of volatile organic compound (VOCs). To extend hydrophobic ILs laboratory performance into commercial process requires the creation of a brief database for biocatalytic reactions. In light of the growing relevance of this theme, the current review intends to address the important biotechnological applications of the frequently employed hydrophobic 1-butyl-3-methylimidazolium hexafluorophosphate ([Bmim] PF6) IL. The review also attempts to describe the comparison of various whole cell biocatalytic reactions using supercritical carbon dioxide (scCO(2)) biphasic systems for product extraction with potentially competitive ILs and other conventional solvents. (C) 2009 Elsevier B.V. All rights reserved
引用
收藏
页码:1 / 12
页数:12
相关论文
共 205 条
[1]   ENZYMATIC CATALYSIS AND DYNAMICS IN LOW-WATER ENVIRONMENTS [J].
AFFLECK, R ;
XU, ZF ;
SUZAWA, V ;
FOCHT, K ;
CLARK, DS ;
DORDICK, JS .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (03) :1100-1104
[2]   High-pressure phase behavior of carbon dioxide with imidazolium-based ionic liquids [J].
Aki, SNVK ;
Mellein, BR ;
Saurer, EM ;
Brennecke, JF .
JOURNAL OF PHYSICAL CHEMISTRY B, 2004, 108 (52) :20355-20365
[3]   Characterizing ionic liquids on the basis of multiple solvation interactions [J].
Anderson, JL ;
Ding, J ;
Welton, T ;
Armstrong, DW .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (47) :14247-14254
[4]   THE ROLE OF SOLVENT VISCOSITY IN THE DYNAMICS OF PROTEIN CONFORMATIONAL-CHANGES [J].
ANSARI, A ;
JONES, CM ;
HENRY, ER ;
HOFRICHTER, J ;
EATON, WA .
SCIENCE, 1992, 256 (5065) :1796-1798
[5]   Solution thermodynamics of imidazolium-based ionic liquids and water [J].
Anthony, JL ;
Maginn, EJ ;
Brennecke, JF .
JOURNAL OF PHYSICAL CHEMISTRY B, 2001, 105 (44) :10942-10949
[6]   Solubilities and thermodynamic properties of gases in the ionic liquid 1-n-butyl-3-methylimidazolium hexafluorophosphate [J].
Anthony, JL ;
Maginn, EJ ;
Brennecke, JF .
JOURNAL OF PHYSICAL CHEMISTRY B, 2002, 106 (29) :7315-7320
[7]   Effect of water activity on the lipase catalyzed esterification of geraniol in ionic liquid [bmim]PF6 [J].
Barahona, D ;
Pfromm, PH ;
Rezac, ME .
BIOTECHNOLOGY AND BIOENGINEERING, 2006, 93 (02) :318-324
[8]  
Barros RJ, 1998, BIOTECHNOL BIOENG, V59, P364
[9]   Stability and activity of immobilised penicillin G amidase in ionic liquids at controlled aw [J].
Basso, A ;
Cantone, S ;
Linda, P ;
Ebert, C .
GREEN CHEMISTRY, 2005, 7 (09) :671-676
[10]   Application of pervaporation for removal of water produced during enzymatic esterification in ionic liquids [J].
Bélafi-Bakó, K ;
Dörmo, N ;
Ulbert, O ;
Gubicza, L .
DESALINATION, 2002, 149 (1-3) :267-268