The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus

被引：81
作者：
Full, Louise E.
Ruisanchez, Cristina
Monaco, Claudia [1 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Fac Med, Kennedy Inst, London W6 8LH, England
来源：
ARTHRITIS RESEARCH & THERAPY | 2009年 / 11卷 / 02期
关键词：
CORONARY-ARTERY-DISEASE; CARDIOVASCULAR-DISEASE; MYOCARDIAL-INFARCTION; RISK-FACTORS; INTIMA-MEDIA; HEART-DISEASE; ACCELERATES ATHEROSCLEROSIS; DENSITY-LIPOPROTEIN; AUTOIMMUNE-DISEASES; DEFICIENT MICE;
D O I：
10.1186/ar2631
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The increased burden of cardiovascular disease in patients with rheumatoid arthritis and systemic lupus erythematosus has recently become the focus of intense investigation. Pro-atherogenic risk factors and dysregulated inflammation are the main culprits, leading to enhanced atherosclerosis in subgroups of patients with inflammatory diseases. Common molecular pathways shared by atherosclerosis and inflammatory disease may be involved. In this review we map the key determinants of the increased incidence of cardiovascular disease in patients with inflammatory diseases at each step of the atherogenesis.
引用
收藏
页数：10
相关论文
共 93 条
[1]   Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease - A randomized trial [J].
Albert, Christine M. ;
Cook, Nancy R. ;
Gaziano, J. Michael ;
Zaharris, Elaine ;
MacFadyen, Jean ;
Danielson, Eleanor ;
Buring, Julie E. ;
Manson, JoAnn E. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 299 (17) :2027-2036
[2]   Effects of repeated infliximab therapy on serum lipid profile in patients with refractory rheumatoid arthritis [J].
Allanore, Y ;
Kahan, A ;
Sellam, J ;
Ekindjian, OG ;
Borderie, D .
CLINICA CHIMICA ACTA, 2006, 365 (1-2) :143-148
[3]   Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease [J].
Aprahamian, T ;
Rifkin, I ;
Bonegio, A ;
Hugel, B ;
Freyssinet, JM ;
Sato, K ;
Castellot, JJ ;
Walsh, K .
JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 199 (08) :1121-1131
[4]   Premature coronary-artery atherosclerosis in systemic lupus erythematosus [J].
Asanuma, Y ;
Oeser, A ;
Shintani, AK ;
Turner, E ;
Olsen, N ;
Fazio, S ;
Linton, MF ;
Raggi, P ;
Stein, CM .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (25) :2407-2415
[5]   Cardiovascular disease in rheumatoid arthritis:: Single-center hospital-based cohort study in France [J].
Assous, Noemie ;
Touze, Emmanuel ;
Meune, Christophe ;
Kahan, Andre ;
Allanore, Yannick .
JOINT BONE SPINE, 2007, 74 (01) :66-72
[6]  
Aubry MC, 2007, J RHEUMATOL, V34, P937
[7]  
Bacon P. A., 2002, Autoimmunity Reviews, V1, P338, DOI 10.1016/S1568-9972(02)00100-3
[8]   Risk of coronary heart disease and stroke in a large British cohort of patients with systemic lupus erythematosus [J].
Bessant, R ;
Hingorani, A ;
Patel, L ;
MacGregor, A ;
Isenberg, DA ;
Rahman, A .
RHEUMATOLOGY, 2004, 43 (07) :924-929
[9]   Influence of glucocorticoids and disease activity on total and high density lipoprotein cholesterol in patients with rheumatoid arthritis [J].
Boers, M ;
Nurmohamed, MT ;
Doelman, CJA ;
Lard, LR ;
Verhoeven, AC ;
Voskuyl, AE ;
Huizinga, TWJ ;
van de Stadt, RJ ;
Dijkmans, BAC ;
van der Linden, S .
ANNALS OF THE RHEUMATIC DISEASES, 2003, 62 (09) :842-845
[10]   Impact of traditional therapies and biologics on cardiovascular diseases in rheumatoid arthritis [J].
Boyer, Jean-Frederic ;
Cantagrel, Alain ;
Constantin, Arnaud .
CURRENT VASCULAR PHARMACOLOGY, 2008, 6 (03) :218-227
12345678910