Cyclodextrin-Based Polysaccharidic Polymers: An Approach for the Drug Delivery

被引：4
|
作者：
Luzardo-Alvarez, Asteria [1 ,2 ]
Sobarzo-Sanchez, Eduardo [1 ]
Blanco-Mendez, Jose [1 ,2 ]
Otero-Espinar, Francisco J. [1 ]
机构：
[1] Univ Santiago de Compostela, Dept Farm & Tecnol Farmaceut, Santiago De Compostela 15782, Spain
[2] Univ Santiago de Compostela, Dept Farm & Tecnol Farmaceut, Santiago De Compostela 27002, Spain
来源：
CURRENT TOPICS IN MEDICINAL CHEMISTRY | 2014年 / 14卷 / 04期
关键词：
Cyclodextrins; drug delivery system; drug solubility; methods of preparation; pharmaceutical applications; polysaccharides; DERIVATIVES BEARING CYCLODEXTRIN; BETA-CYCLODEXTRIN; ALPHA-CYCLODEXTRIN; MODIFIED CHITOSAN; INCLUSION PROPERTY; HYDROGELS; DEXTRAN; RELEASE; NANOPARTICLES; SYSTEMS;
D O I：
10.2174/1568026613666131219125419
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The aim of the present review is to give an overview of a new class of polysaccharidic CD-based systems and to address the use of these systems in drug delivery. First, we review miscellaneous methods to obtain and synthesize the structural modification of natural polysaccharides, mainly, with cyclodextrins. In a second part of this review, we provide a summary of recent findings not only in the field of drug delivery, but in also how these systems have displayed different applications in the biomedical and pharmaceutical fields.
引用
收藏
页码：542 / 551
页数：10
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