Intestinal transplantation for motility disorders

被引：15

作者：

Millar, Alastair J. W. ^{[1
,2
]}

Gupte, Girish ^{[3
]}

Sharif, Khalid ^{[3
]}

机构：

[1] Univ Cape Town, ZA-7925 Cape Town, South Africa

[2] Red Cross War Mem Childrens Hosp, Cape Town, South Africa

[3] Birmingham Childrens Hosp, Liver Unit, Birmingham, W Midlands, England

来源：

SEMINARS IN PEDIATRIC SURGERY | 2009年 / 18卷 / 04期

关键词：

Dysmotility; Intestinal transplantation; Children; CHILDREN; PSEUDOOBSTRUCTION; BOWEL; GROWTH; LIVER;

D O I：

10.1053/j.sempedsurg.2009.07.007

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Intestinal transplantation (ITx) has now become an accepted form of replacement therapy for intestinal failure (IF) and its complications. Disorders of bowel motility may represent up to 25% of patients on waiting lists for ITx. Some patients with short bowel as a cause for IF may also have dysmotile bowel. Underlying pathology of the intestine is heterogenous and may be due to abnormalities in the nerve Supply, intestinal smooth muscle, or may be regarded as idiopathic (chronic intestinal pseudo-obstruction). Outcome after ITx for dysmotility has previously been guarded, but providing the appropriate craft is used and taking into account the functional motility of residual bowel, it should not be different from other indications. The subject is reviewed emphasizing the potential pitfalls in case selection and management. The results of the ITx unit in Birmingham, UK are briefly reviewed. (C) 2009 Published by Elsevier Inc.

引用

页码：258 / 262

页数：5

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