Severe Acute Chest Syndrome in a Sickle Cell Patient That Required Repeated Exchange Transfusion

被引：0

作者：

Saleh, Mohammed ^{[1
,2
]}

Asemota, Joseph ^{[2
,3
,4
]}

机构：

[1] Univ Missouri, Internal Med, Columbia, MO 65211 USA

[2] Howard Univ Hosp, Internal Med, Washington, DC 20060 USA

[3] St Georges Univ, Sch Med, Clin Anat, True Blue, Grenada

[4] Harvard Med Sch, Hematol Oncol, Beth Israel Deaconess Med Ctr, Boston, MA 02115 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2021年 / 13卷 / 02期

关键词：

sickle cell disease; acute chest syndrome; exchange transfusion; packed red blood cell transfusion; severe respiratory failure; ADHESION;

D O I：

10.7759/cureus.13066

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acute chest syndrome (ACS) is one of the major causes of mortality and morbidity in patients with sickle cell disease (SCD). ACS usually presents in a more severe form in adults older than 20 years. High clinical suspicion should be maintained in SCD patients who presents with painful crises. This case report presents an interesting severe form of ACS that, quite unusually, required repeated exchanged blood transfusion to achieve clinical improvement.

引用

页数：3

共 11 条

[1] NITRIC-OXIDE DECREASES CYTOKINE-INDUCED ENDOTHELIAL ACTIVATION - NITRIC-OXIDE SELECTIVELY REDUCES ENDOTHELIAL EXPRESSION OF ADHESION MOLECULES AND PROINFLAMMATORY CYTOKINES [J].