α-amylase inhibitors from Roselle (Hibiscus sabdariffa Linn.) tea

被引:152
作者
Hansawasdi, C [1 ]
Kawabata, J [1 ]
Kasai, T [1 ]
机构
[1] Hokkaido Univ, Lab Food Biochem, Div Appl Biosci, Grad Sch Agr,Kita Ku, Sapporo, Hokkaido 0608589, Japan
关键词
porcine pancreatic alpha-amylase inhibitor; roselle; Hibiscus sabdariffa;
D O I
10.1271/bbb.64.1041
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A roselle (Hibiscus sabdariffa Linn.) tea extract was found to have high inhibitory activity against porcine pancreatic or-amylase. Hibiscus acid and its 6-methyl ester were respectively isolated as active principles from the 50% methanol and acetone extracts of roselle tea. The activity of each isolate was compared to that of structurally related citric acid, a previously known inhibitor of fungal alpha-amylase.
引用
收藏
页码:1041 / 1043
页数:3
相关论文
共 22 条
  • [1] ALI FS, 1989, ZBL MIKROBIOL, V144, P623
  • [2] BACHSTEZ M, 1948, CIENCIA, V9, P121
  • [3] Acarbose and 1-deoxynojirimycin inhibit maltose and maltooligosaccharide hydrolysis of human small intestinal glucoamylase-maltase in two different substrate-induced modes
    Breitmeier, D
    Gunther, S
    Heymann, H
    [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1997, 346 (01) : 7 - 14
  • [4] THE PREVENTION OF CELL-ADHESION AND THE CELL-TO-CELL SPREAD OF HIV-1 IN-VITRO BY THE ALPHA-GLUCOSIDASE-1 INHIBITOR, 6-O-BUTANOYL CASTANOSPERMINE (MDL-28574)
    BRIDGES, CG
    BRENNAN, TM
    TAYLOR, DL
    MCPHERSON, M
    TYMS, AS
    [J]. ANTIVIRAL RESEARCH, 1994, 25 (02) : 169 - 175
  • [5] N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with changes in antibody recognition of the V1/V2 region of gp120
    Fischer, PB
    Karlsson, GB
    Butters, TD
    Dwek, RA
    Platt, FM
    [J]. JOURNAL OF VIROLOGY, 1996, 70 (10) : 7143 - 7152
  • [6] N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with impaired gp120 shedding and gp41 exposure
    Fischer, PB
    Karlsson, GB
    Dwek, RA
    Platt, FM
    [J]. JOURNAL OF VIROLOGY, 1996, 70 (10) : 7153 - 7160
  • [7] GREENWOOD MR, 1981, AM J PHYSIOL, V240, P72
  • [8] Griebel C, 1939, UNTERSUCH LEBENSM, V77, P561
  • [9] Griebel C., 1942, UNTERSUCH LEBENSM, V83, P481
  • [10] Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent -: A randomized controlled trial
    Heymsfield, SB
    Allison, DB
    Vasselli, JR
    Pietrobelli, A
    Greenfield, D
    Nunez, C
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (18): : 1596 - 1600