Botulinum toxin A as treatment for drooling saliva in PD

被引:144
作者
Pal, PK [1 ]
Calne, DB [1 ]
Calne, S [1 ]
Tsui, JKC [1 ]
机构
[1] UBC Hosp, Ctr Neurodegenerat Disorders, Vancouver, BC, Canada
关键词
botulinum toxin A; saliva; drooling; PD;
D O I
10.1212/WNL.54.1.244
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors evaluated intraparotid injections of botulinum toxin A in reducing salivary secretions and drooling in nine patients with PD. There was a marked objective reduction in secretion, and two thirds of the patients had subjective improvement in drooling. No side effects were observed. The authors conclude that botulinum toxin A promises to be a simple and effective treatment for the common problem of drooling saliva in chronic neurologic disease.
引用
收藏
页码:244 / 247
页数:4
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