The regioselective preparation of 1,3-diketones

被引：44
作者：
Wiles, C
Watts, P
Haswell, SJ
Pombo-Villar, E
机构：
[1] Univ Hull, Dept Chem, Fac Sci & Environm, Kingston Upon Hull HU6 7RX, N Humberside, England
[2] Novartis Pharma Ltd, Nervous Syst Res, CH-4002 Basel, Switzerland
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 16期
关键词：
acylation; silyl enol ethers; enolates; regioselectivity;
D O I：
10.1016/S0040-4039(02)00432-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The regioselectivity of the acylation of Li enolates and silyl enol ethers is reported using acyl halides and acyl cyanides. We illustrate a simple method for the preparation of 1,3-diketones via the silyl enol ether in excellent yields. free from competing O-acylation and diacylation products. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：2945 / 2948
页数：4
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