Electrochemical determination of serotonin and the competitive adsorption with dopamine at 5,5-ditetradecyl-2-(2-trimethylammonioethyl)-1,3-dioxane bromide lipid film modified by glassy carbon electrode

被引：16

作者：

Gong, JM ^{[1
]}

Lin, XQ ^{[1
]}

机构：

[1] Univ Sci & Technol China, Hefei 230026, Peoples R China

来源：

ANALYTICAL SCIENCES | 2004年 / 20卷 / 06期

关键词：

D O I：

10.2116/analsci.20.905

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel and effective approach to sensitively determine serotonin, known as 5-hydroxytryptamine (5-HT), has been proposed based on a 5,5-ditetradecyl-2-(2-trimethylammonioethyl)-1,3-dioxane bromide (DTDB) self-assembled lipid bilayer membrane modified glassy carbon electrode (DTDB/GCE). A DTDB/GCE shows the strong electrocatalysis for the oxidation of 5-HT, with the peak potential shifted to less positive value of 0.376 V vs. SCE, and effectively eliminates the interference from ascorbic acid (AA), even in the presence of 100-fold concentration of AA. Differential pulse voltammetry (DPV) gave a linear current for 5-HT from 2.0 x 10(-7) to 1.0 x 10(-5) M. At the DTDB/GCE, the oxidation of 5-HT was controlled by the adsorption process; for 5-HT coexisting with DA, the competitive adsorption was observed.

引用

页码：905 / 909

页数：5

共 36 条

[1] CHARGE-TRANSFER AT PARTIALLY BLOCKED SURFACES - A MODEL FOR THE CASE OF MICROSCOPIC ACTIVE AND INACTIVE SITES [J].

AMATORE, C ;

SAVEANT, JM ;

TESSIER, D .

JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1983, 147 (1-2) :39-51

[2] Voltammetric detection of the polycation protamine by the use of electrodes modified with self-assembled monolayers of thioctic acid [J].

Gadzekpo, VPY ;

Xiao, KP ;

Aoki, H ;

Bühlmann, P ;

Umezawa, Y .

ANALYTICAL CHEMISTRY, 1999, 71 (22) :5109-5115

[3] Fabrication and photoelectric properties of self-assembled bilayer lipid membranes on conducting glass [J].

Gao, H ;

Luo, GA ;

Feng, J ;

Ottova, AL ;

Tien, HT .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2000, 59 (1-3) :87-91

[4] Serotonin-Cu(II)-mediated DNA cleavage: mechanism of copper binding by serotonin [J].

Hadi, N ;

Malik, A ;

Azam, S ;

Khan, NU ;

Iqbal, J .

TOXICOLOGY IN VITRO, 2002, 16 (06) :669-674

[5] Defect formation induced by PAMAM dendrimers on Pt-supported bilayer lipid membranes investigated by electrochemistry [J].

Huang, WM ;

Han, XJ ;

Wang, EK .

JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 2003, 150 (04) :E218-E221

[6] Determination of monoamine transmitters and their metabolites by capillary electrophoresis with electrochemical detection [J].

Jin, W ;

Jin, LT ;

Shi, GY ;

Ye, JN .

ANALYTICA CHIMICA ACTA, 1999, 382 (1-2) :33-37

[7] Homooxacalix[3]arene derivatives as ionophores for serotonin-selective membrane electrodes [J].

Katsu, T ;

Ido, K ;

Sagara, S ;

Tsubaki, K ;

Fuji, K .

ELECTROANALYSIS, 2003, 15 (04) :287-293

[8] Biogenic amine-sensitive membrane electrodes using the hydrogen bond-forming ability of solvent mediators [J].

Katsu, T ;

Hirodo, H .

ANALYTICAL SCIENCES, 2000, 16 (08) :789-793

[9] DEPOSITION OF METALLIC AND SEMICONDUCTING LAYERS ONTO BILAYER LIPID-MEMBRANES [J].

KUTNIK, J ;

TIEN, HT .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1987, 46 (03) :413-419

[10] Electrocatalytic oxidation and selective detection of dopamine at a 5,5-ditetradecyl-2-(2-trimethyl-ammonioethyl)-1,3-dioxane bromide self-assembled bilayer membrane modified glassy carbon electrode [J].

Lin, XQ ;

Gong, JM .

ANALYTICA CHIMICA ACTA, 2004, 507 (02) :255-261

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