Pancreatic Adenocarcinoma, Version 2.2014 Featured Updates to the NCCN Guidelines

被引：269

作者：

Tempero, Margaret A. ^{[1
]}

Malafa, Mokenge P. ^{[2
]}

Behrman, Stephen W. ^{[3
]}

Benson, Al B., III ^{[4
]}

Casper, Ephraim S. ^{[5
]}

Chiorean, E. Gabriela ^{[6
]}

Chung, Vincent ^{[7
]}

Cohen, Steven J. ^{[8
]}

Czito, Brian ^{[9
]}

Engebretson, Anitra ^{[10
]}

Feng, Mary ^{[11
]}

Hawkins, William G. ^{[12
,13
]}

Herman, Joseph ^{[14
]}

Hoffman, John P. ^{[8
]}

Ko, Andrew ^{[1
]}

Komanduri, MDSrinadh ^{[4
]}

Koong, Albert ^{[15
]}

Lowy, Andrew M. ^{[16
]}

Ma, Wen Wee ^{[17
]}

Merchant, Nipun B. ^{[18
]}

Mulvihill, Sean J. ^{[19
]}

Muscarella, Peter, II ^{[20
,21
]}

Nakakura, Eric K. ^{[1
]}

Obando, Jorge ^{[9
]}

Pitman, Martha B. ^{[22
]}

Reddy, Sushanth ^{[23
]}

Sasson, Aaron R. ^{[24
]}

Thayer, Sarah P. ^{[22
]}

Weekes, Colin D. ^{[25
]}

Wolff, Robert A. ^{[26
]}

Wolpin, Brian M. ^{[27
]}

Burns, Jennifer L. ^{[28
]}

Freedman-Cass, Deborah A. ^{[28
]}

机构：

[1] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA

[2] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[3] Univ Tennessee, Hlth Sci Ctr, St Jude Childrens Res Hosp, Knoxville, TN 37996 USA

[4] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[5] Mem Sloan Kettering Canc Ctr, New York, NY USA

[6] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, Seattle, WA USA

[7] City Hope Comprehens Canc Ctr, Duarte, CA USA

[8] Fox Chase Canc Ctr, Philadelphia, PA USA

[9] Duke Canc Inst, Durham, NC USA

[10] PanCAN, Chicago, IL USA

[11] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[12] Univ Washington, Med Ctr, Seattle, WA 98195 USA

[13] Barnes Jewish Hosp, Siteman Canc Ctr, Seattle, WA 98195 USA

[14] Johns Hopkins Univ Hosp, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD 21287 USA

[15] Stanford Canc Inst, Stanford, CA USA

[16] Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92093 USA

[17] Roswell Pk Canc Inst, Buffalo, NY USA

[18] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[19] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[20] Ohio State Univ, Ctr Comprehens Canc, Columbus, OH 43210 USA

[21] James Canc Hosp & Solove Res Inst, Columbus, OH USA

[22] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA

[23] Univ Alabama, Birmingham Comprehens Canc Ctr, Tuscaloosa, AL 35487 USA

[24] Nebraska Med Ctr, Fred & Pamela Buffett Canc Ctr, Omaha, NE USA

[25] Univ Colorado, Ctr Canc, Boulder, CO 80309 USA

[26] Univ Texas MD Anderson Canc Ctr, Houston, TX USA

[27] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[28] Natl Comprehens Canc Network, Ft Washington, PA USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2014年 / 12卷 / 08期

关键词：

GEMCITABINE PLUS RADIOTHERAPY; NEOADJUVANT THERAPY; PHASE-II; RADIATION-THERAPY; PREOPERATIVE CHEMORADIATION; ADJUVANT CHEMOTHERAPY; SURGICAL RESECTION; CANCER; CHEMORADIOTHERAPY; TRIAL;

D O I：

10.6004/jnccn.2014.0106

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The NCCN Guidelines for Pancreatic Adenocarcinoma discuss the diagnosis and management of adenocarcinomas of the exocrine pancreas and are intended to assist with clinical decision-making. These NCCN Guidelines Insights summarize major discussion points from the 2014 NCCN Pancreatic Adenocarcinoma Panel meeting. The panel discussion focused mainly on the management of borderline resectable and locally advanced disease. In particular, the panel discussed the definition of borderline resectable disease, role of neoadjuvant therapy in borderline disease, role of chemoradiation in locally advanced disease, and potential role of newer, more active chemotherapy regimens in both settings.

引用

页码：1083 / 1093

页数：11

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