Introduction to the Special Sectionon Epigenetics

被引:45
作者
Lester, Barry M. [1 ,2 ]
Conradt, Elisabeth [3 ]
Marsit, Carmen [4 ]
机构
[1] Brown Univ, Alpert Med Sch, Providence, RI 02912 USA
[2] Women & Infants Hosp Rhode Isl, Providence, RI USA
[3] Univ Utah, Salt Lake City, UT 84112 USA
[4] Geisel Sch Med Dartmouth, Dartmouth, NS, Canada
关键词
RECEPTOR GENE PROMOTER; PITUITARY-ADRENAL AXIS; DNA METHYLATION; MATERNAL-CARE; STRESS; EXPOSURE; DEPRESSION; CHILDHOOD; ADVERSITY; OXYTOCIN;
D O I
10.1111/cdev.12489
中图分类号
G44 [教育心理学];
学科分类号
0402 ; 040202 ;
摘要
Epigenetics provides the opportunity to revolutionize our understanding of the role of genetics and the environment in explaining human behavior, although the use of epigenetics to study human behavior is just beginning. In this introduction, the authors present the basics of epigenetics in a way that is designed to make this exciting field accessible to a wide readership. The authors describe the history of human behavioral epigenetic research in the context of other disciplines and graphically illustrate the burgeoning of research in the application of epigenetic methods and principles to the study of human behavior. The role of epigenetics in normal embryonic development and the influence of biological and environmental factors altering behavior through epigenetic mechanisms and developmental programming are discussed. Some basic approaches to the study of epigenetics are reviewed. The authors conclude with a discussion of challenges and opportunities, including intervention, as the field of human behavioral epigenetics continue to grow.
引用
收藏
页码:29 / 37
页数:9
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