Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds

被引：16

作者：

Ippel, Bastiaan D. ^{[1
,2
]}

Van Haaften, Eline E. ^{[1
,2
]}

Bouten, Carlijn V. C. ^{[1
,2
]}

Dankers, Patricia Y. W. ^{[2
,3
]}

机构：

[1] Eindhoven Univ Technol, Inst Complex Mol Syst, NL-5600 MB Eindhoven, Netherlands

[2] Eindhoven Univ Technol, Dept Biomed Engn, Lab Cell & Tissue Engn, NL-5600 MB Eindhoven, Netherlands

[3] Eindhoven Univ Technol, Inst Complex Mol Syst, Lab Cell & Tissue Engn, Dept Biomed Engn, NL-5600 MB Eindhoven, Netherlands

来源：

ACS APPLIED POLYMER MATERIALS | 2020年 / 2卷 / 09期

基金：

欧洲研究理事会;

关键词：

supramolecular chemistry; additives; electrospinning; multiscale; mechanics; biomaterials; THERMOPLASTIC ELASTOMERS; MOLECULAR RECOGNITION; FIBER;

D O I：

10.1021/acsapm.0c00658

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The mechanical properties of scaffolds used for mechanically challenging applications such as cardiovascular implants are unequivocally important. Here, the effect of supramolecular additive functionalization on mechanical behavior of electrospun scaffolds was investigated for one bisurea-based model additive and two previously developed antifouling additives. The model additive has no effect on the mechanical properties of the bulk material, whereas the stiffness of electrospun scaffolds was slightly decreased compared to pristine PCL-BU following the addition of the three different additives. These results show the robustness of supramolecular additives used in biomedical applications, in which mechanical properties are important, such as vascular grafts and heart valve constructs.

引用

页码：3742 / 3748

页数：7

共 34 条

[1] Elastomeric Electrospun Polyurethane Scaffolds: The Interrelationship Between Fabrication Conditions, Fiber Topology, and Mechanical Properties [J].

Amoroso, Nicholas J. ;

D'Amore, Antonio ;

Hong, Yi ;

Wagner, William R. ;

Sacks, Michael S. .

ADVANCED MATERIALS, 2011, 23 (01) :106-+

[2] Multi-scale mechanical characterization of scaffolds for heart valve tissue engineering [J].

Argento, G. ;

Simonet, M. ;

Oomens, C. W. J. ;

Baaijens, F. P. T. .

JOURNAL OF BIOMECHANICS, 2012, 45 (16) :2893-2898

[3] Mechanical behavior of self-assembled carbon nanotube reinforced nylon 6,6 fibers [J].

Baji, Avinash ;

Mai, Yiu-Wing ;

Wong, Shing-Chung ;

Abtahi, Mojtaba ;

Du, Xusheng .

COMPOSITES SCIENCE AND TECHNOLOGY, 2010, 70 (09) :1401-1409

[4] Molecular recognition in bisurea thermoplastic elastomers studied with pyrene-based fluorescent probes and atomic force microscopy [J].

Botterhuis, Nicole E. ;

Karthikeyan, S. ;

Veldman, Dirk ;

Meskers, Stefan C. J. ;

Sijbesma, Rint P. .

CHEMICAL COMMUNICATIONS, 2008, (33) :3915-3917

[5] Self-Sorting of Guests and Hard Blocks in Bisurea-Based Thermoplastic Elastomers [J].

Botterhuis, Nicole E. ;

Karthikeyan, S. ;

Spiering, A. J. H. ;

Sijbesma, Rint P. .

MACROMOLECULES, 2010, 43 (02) :745-751

[6] From single fiber to macro-level mechanics: A structural finite-element model for elastomeric fibrous biomaterials [J].

D'Amore, Antonio ;

Amoroso, Nicholas ;

Gottardi, Riccardo ;

Hobson, Christopher ;

Carruthers, Christopher ;

Watkins, Simon ;

Wagner, William R. ;

Sacks, Michael S. .

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 2014, 39 :146-161

[7]

Duijvelshoff Renee, 2018, Bioengineering-Basel, V5, P61, DOI 10.3390/bioengineering5030061

[8]

Filonenko G. A., 2018, ANGEW CHEM, V130, P16623

[9] Dynamic Phosphorescent Probe for Facile and Reversible Stress Sensing [J].

Filonenko, Georgy A. ;

Khusnutdinova, Julia R. .

ADVANCED MATERIALS, 2017, 29 (22)

[10] Efficient Functionalization of Additives at Supramolecular Material Surfaces [J].

Goor, Olga J. G. M. ;

Keizer, Henk M. ;

Bruinen, Anne L. ;

Schmitz, Moniek G. J. ;

Versteegen, Ron M. ;

Janssen, Henk M. ;

Heeren, Ron M. A. ;

Dankers, Patricia Y. W. .

ADVANCED MATERIALS, 2017, 29 (05)

← 1 2 3 4 →