Hantavirus cardiopulmonary syndrome: immune response and pathogenesis

被引：48
作者：
Borges, Alessandra A.
Campos, Gelse M.
Moreli, Marcos L.
Souza, Ricardo L. M.
Aquino, Victor H.
Saggioro, Fabiano P.
Figueiredo, Luiz T. M.
机构：
[1] Univ Sao Paulo, Sch Med Ribeirao Preto, Virol Res Ctr, BR-14049900 Sao Paulo, Brazil
[2] Univ Sao Paulo, Sch Med Ribeirao Preto, Dept Pathol, BR-14049900 Sao Paulo, Brazil
来源：
MICROBES AND INFECTION | 2006年 / 8卷 / 08期
关键词：
hantavirus; cardiopulmonary syndrome; beta; 3; integrin; neutralizing antibodies; interferons; cellular immunity; interleukins; human leukocyte antigen; pathogenesis;
D O I：
10.1016/j.micinf.2006.04.019
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Hantaviruses are emerging viruses in the Americas that cause cardiopulmonary syndrome with high lethality. The intense cellular immune response to hantavirus alters normal endothelial cell barrier functions and seems to be harmful to the host. On the other hand, the humoral immune response seems to be essential for recovery from infection. (c) 2006 Elsevier SAS. All rights reserved.
引用
收藏
页码：2324 / 2330
页数：7
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