mTOR kinase inhibitor sensitizes T-cell lymphoblastic leukemia for chemotherapy-induced DNA damage via suppressing FANCD2 expression

被引:13
作者
Guo, F. [1 ]
Li, J. [1 ]
Zhang, S. [1 ]
Du, W. [1 ]
Amarachintha, S. [1 ]
Sipple, J. [1 ]
Phelan, J. [2 ]
Grimes, H. L. [2 ]
Zheng, Y. [1 ]
Pang, Q. [1 ]
机构
[1] Cincinnati Childrens Hosp Med Ctr, Div Expt Hematol & Canc Biol, Cincinnati, OH 45229 USA
[2] Cincinnati Childrens Hosp Med Ctr, Div Immunobiol, Cincinnati, OH 45229 USA
关键词
MAMMALIAN TARGET; RAPAMYCIN; PATHWAY; CANCER;
D O I
10.1038/leu.2013.215
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:203 / 206
页数:4
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