Chlamydia pneumoniae in atherosclerosis

被引：42

作者：

Saikku, P ^{[1
]}

机构：

[1] Natl Publ Hlth Inst, KTL, Dept Oulu, Oulu, Finland

来源：

JOURNAL OF INTERNAL MEDICINE | 2000年 / 247卷 / 03期

关键词：

atherosclerosis; Chlamydia pneumoniae; infection; pathogenesis;

D O I：

10.1046/j.1365-2796.2000.00659.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chlamydia pneumoniae is currently the infectious agent most often associated with the inflammation found in atherosclerosis. The seroepidemiological association and the actual presence of pathogen in lesions has been confirmed in numerous studies, in which technical difficulties seem to be the only limitation. Besides animal experiments and intervention trials, we need information of possible pathogenic mechanisms. Recently, several studies have suggested mechanisms by which C. pneumoniae infection could participate in the development of atherosclerosis.

引用

页码：391 / 396

页数：6

共 66 条

[1] Randomized secondary prevention trial of azithromycin in patients with coronary artery disease and serological evidence for Chlamydia pneumoniae infection -: The azithromycin in coronary artery disease:: Elimination of myocardial infection with Chlamydia (ACADEMIC) study [J].