Cyclopentenone prostaglandins - new allies in the war on inflammation

被引：42

作者：

Willoughby, DA ^{[1
]}

Moore, AR ^{[1
]}

Colville-Nash, PR ^{[1
]}

机构：

[1] St Bartholomews & Royal London Sch Med & Dent, Dept Expt Pathol, London EC1M 6BQ, England

来源：

NATURE MEDICINE | 2000年 / 6卷 / 02期

关键词：

D O I：

10.1038/72224

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Although the effects of anti-inflammatory drugs have been well studied, little is known about the signaling pathways involved in the inflammatory response. The recent finding that cyclopentenone prostaglandins inhibit IκB kinase provides a new explanation for the anti-inflammatory effects of these molecules.

引用

页码：137 / 138

页数：2

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