A general and practical Ni-catalyzed C-H perfluoroalkylation of (hetero)arenes

被引：25

作者：

Zhang, Shaoke ^{[1
]}

Rotta-Loria, Nicolas ^{[2
]}

Weniger, Florian ^{[1
]}

Rabeah, Jabor ^{[1
]}

Neumann, Helfried ^{[1
]}

Taeschler, Christoph ^{[3
]}

Beller, Matthias ^{[1
]}

机构：

[1] Univ Rostock eV, Leibniz Inst Katalyse, Albert Einstein Str 29a, D-18059 Rostock, Germany

[2] Dalhousie Univ Halifax, Dept Chem, Halifax, NS B3H 4R2, Canada

[3] Lonza Ltd, Rottenstr 6, CH-3930 Visp, Switzerland

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 47期

关键词：

HETEROAROMATIC-COMPOUNDS; AROMATIC-COMPOUNDS; OXIDATIVE TRIFLUOROMETHYLATION; FLUORINE; FLUOROALKYLATION; ARENES; CHLORIDES; PRECATALYST; CHEMISTRY; INSIGHTS;

D O I：

10.1039/c9cc01971e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A direct perfluoroalkylation of (hetero) arenes using the air- and moisture-stable complex (dppf)Ni(o-tol)Cl was developed (23 examples). The novel procedure allows for the synthesis of various fluorinated products and tolerates sensitive functional groups including aldehydes, free amino groups and several heterocycles.

引用

页码：6723 / 6726

页数：4

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