The influence of maternal and infant nutrition on cardiometabolic traits: novel findings and future research directions from four Canadian birth cohort studies

被引:4
作者
de Souza, R. J. [1 ,2 ]
Zulyniak, M. A. [3 ]
Stearns, J. C. [4 ,5 ]
Wahi, G. [6 ]
Teo, K. [1 ,2 ,4 ]
Gupta, M. [4 ,7 ]
Sears, M. R. [4 ]
Subbarao, P. [8 ,9 ]
Anand, S. S. [1 ,2 ,4 ]
机构
[1] McMaster Univ, Fac Hlth Sci, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada
[2] Populat Hlth Res Inst, Hamilton, ON, Canada
[3] Univ Leeds, Sch Food Sci & Nutr, Leeds, W Yorkshire, England
[4] McMaster Univ, Dept Med, Hamilton, ON, Canada
[5] Farncombe Family Digest Hlth Res Inst, Hamilton, ON, Canada
[6] McMaster Univ, Dept Pediat, Hamilton, ON, Canada
[7] Canadian Collaborat Res Network, Brampton, ON, Canada
[8] Univ Toronto, Dept Pediat, Toronto, ON, Canada
[9] Hosp Sick Children, Toronto, ON, Canada
基金
加拿大健康研究院;
关键词
Birth cohort; Microbiome; Birth weight; Nutrition; Diet; Pregnancy; CORONARY-HEART-DISEASE; DIETARY PATTERN-ANALYSIS; DUTCH HUNGER WINTER; DEVELOPMENTAL ORIGINS; CARDIOVASCULAR-DISEASE; METABOLIC SYNDROME; PANCREATIC-CANCER; FOOD-CONSUMPTION; GUT MICROBIOME; RISK;
D O I
10.1017/S0029665119000612
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
A mother's nutritional choices while pregnant may have a great influence on her baby's development in the womb and during infancy. There is evidence that what a mother eats during pregnancy interacts with her genes to affect her child's susceptibility to poor health outcomes including childhood obesity, pre-diabetes, allergy and asthma. Furthermore, after what an infant eats can change his or her intestinal bacteria, which can further influence the development of these poor outcomes. In the present paper, we review the importance of birth cohorts, the formation and early findings from a multi-ethnic birth cohort alliance in Canada and summarise our future research directions for this birth cohort alliance. We summarise a method for harmonising collection and analysis of self-reported dietary data across multiple cohorts and provide examples of how this birth cohort alliance has contributed to our understanding of gestational diabetes risk; ethnic and diet-influences differences in the healthy infant microbiome; and the interplay between diet, ethnicity and birth weight. Ongoing work in this birth cohort alliance will focus on the use of metabolomic profiling to measure dietary intake, discovery of unique diet-gene and diet-epigenome interactions, and qualitative interviews with families of children at risk of metabolic syndrome. Our findings to-date and future areas of research will advance the evidence base that informs dietary guidelines in pregnancy, infancy and childhood, and will be relevant to diverse and high-risk populations of Canada and other high-income countries.
引用
收藏
页码:351 / 361
页数:11
相关论文
共 114 条
[1]   Are child eating patterns being transformed globally? [J].
Adair, LS ;
Popkin, BM .
OBESITY RESEARCH, 2005, 13 (07) :1281-1299
[2]   Interplay of early-life nutritional programming on obesity, inflammation and epigenetic outcomes [J].
Alfredo Martinez, J. ;
Cordero, Paul ;
Campion, Javier ;
Milagro, Fermin I. .
PROCEEDINGS OF THE NUTRITION SOCIETY, 2012, 71 (02) :276-283
[3]  
Anand Sonia S, 2017, CMAJ Open, V5, pE604, DOI 10.9778/cmajo.20170027
[4]   Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study [J].
Anand, Sonia S. ;
Vasudevan, Anil ;
Gupta, Milan ;
Morrison, Katherine ;
Kurpad, Anura ;
Teo, Koon K. ;
Srinivasan, Krishnamachari .
BMC PUBLIC HEALTH, 2013, 13
[5]   Differences in risk factors, atherosclerosis, and cardiovascular disease between ethnic groups in Canada: the Study of Health Assessment and Risk in Ethnic groups (SHARE) [J].
Anand, SS ;
Yusuf, S ;
Vuksan, V ;
Devanesen, S ;
Teo, KK ;
Montague, PA ;
Kelemen, L ;
Yi, CL ;
Lonn, E ;
Gerstein, H ;
Hegele, RA ;
McQueen, M .
LANCET, 2000, 356 (9226) :279-284
[6]  
[Anonymous], 1989, Diet and health: implications for reducing chronic disease risk
[7]  
[Anonymous], 2016, Global status Report on Blood Safety and Availability
[8]  
[Anonymous], PEDIATRICS
[9]  
[Anonymous], 2015, DIETARY GUIDELINES A
[10]   The gut microbiome, diet, and links to cardiometabolic and chronic disorders [J].
Aron-Wisnewsky, Judith ;
Clement, Karine .
NATURE REVIEWS NEPHROLOGY, 2016, 12 (03) :169-181