The application of capillary electrophoresis techniques in toxicological analysis

被引:11
|
作者
Sieradzka, Ewelina [1 ]
Witt, Katarzyna [2 ]
Milnerowicz, Halina [1 ]
机构
[1] Wroclaw Med Univ, Fac Pharm, Dept Biomed & Environm Anal, Wroclaw, Poland
[2] Wroclaw Med Univ, Fac Pharm, Dept Biomed & Environm Anal, Students Sci Assoc, Wroclaw, Poland
关键词
capillary electrophoresis; toxicological analysis; drug; poisoning; overdose; DIODE-INDUCED FLUORESCENCE; LIQUID-CHROMATOGRAPHY; GEL-ELECTROPHORESIS; BIOLOGICAL SAMPLES; HERBAL MEDICINES; DRUGS; SEPARATION; CE; ANTIDEPRESSANTS; MICROEMULSION;
D O I
10.1002/bmc.3234
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Capillary electrophoresis (CE) comprises a group of techniques used to separate chemical mixtures. Analytical separation is based on different electrophoretic mobilities, thereby allowing qualitative and quantitative evaluations to be made. The application of CE in medical science, especially in toxicological studies, is developing rapidly because of the short time required for analysis and its high sensitivity, selectivity and ability to determine substances of an acidic, alkaline and neutral character. This review focuses on the possibility of applying CE in toxicological analysis. Advances in different CE analyses and detection techniques connected with this method are described. Copyright (c) 2014 John Wiley & Sons, Ltd.
引用
收藏
页码:1507 / 1513
页数:7
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