An optimized extraction technique for acetylcholinesterase inhibitors from the Camellia japonica seed cake by using response surface methodology

被引：7

作者：

Kim, Jae Kyeom ^{[1
]}

Kim, Cho Rong ^{[2
]}

Lim, Ho-Jeong ^{[3
]}

Nam, Sang Hae ^{[3
]}

Joo, Ok Soo ^{[3
]}

Shin, Dong-Hoon ^{[2
]}

Shin, Eui-Cheol ^{[3
]}

机构：

[1] Univ Minnesota, Dept Food Sci & Nutr, St Paul, MN USA

[2] Korea Univ, Dept Food & Biotechnol, Seoul, South Korea

[3] Gyeongnam Natl Univ Sci & Technol, Dept Food Sci, Jinju, South Korea

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2014年 / 78卷 / 07期

关键词：

Camellia japonica; camellia seed cake; acetylcholinesterase; Alzheimer's disease; response surface methodology; ALZHEIMER-DISEASE; OIL; PHYTOCHEMICALS; IMPAIRMENT; FLAVONOIDS; OLEIFERA; RISK; MICE;

D O I：

10.1080/09168451.2014.915723

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The response surface methodology (RSM) was used to optimize the extraction conditions for the acetylcholinesterase (AchE) inhibitory activity and extraction yield from Camellia japonica seed cake. Predicted values for AchE inhibition and extraction yield were 19.41 and 13.35%, respectively, which are in good agreement with the experimental values from validation, suggesting that RSM may provide a useful tool to optimization processes.

引用

页码：1237 / 1241

页数：5

共 22 条

[1] Response surface methodology (RSM) as a tool for optimization in analytical chemistry [J].

Bezerra, Marcos Almeida ;

Santelli, Ricardo Erthal ;

Oliveira, Eliane Padua ;

Villar, Leonardo Silveira ;

Escaleira, Luciane Amlia .

TALANTA, 2008, 76 (05) :965-977

[2] The history of the cholinergic hypothesis [J].

Contestabile, Antonio .

BEHAVIOURAL BRAIN RESEARCH, 2011, 221 (02) :334-340

[3] Antioxidant phytochemicals against type 2 diabetes [J].

Dembinska-Kiec, Aldona ;

Mykkanen, Otto ;

Kiec-Wilk, Beata ;

Mykkanen, Hannu .

BRITISH JOURNAL OF NUTRITION, 2008, 99 :ES109-ES117

[4] Optimization and evaluation of acetylcholine esterase immobilization on ceramic packing using response surface methodology [J].

Ebrahimi, B. ;

Shojaosadati, S. A. ;

Ranaie, S. O. ;

Mousavi, S. M. .

PROCESS BIOCHEMISTRY, 2010, 45 (01) :81-87

[5] A NEW AND RAPID COLORIMETRIC DETERMINATION OF ACETYLCHOLINESTERASE ACTIVITY [J].

ELLMAN, GL ;

COURTNEY, KD ;

ANDRES, V ;

FEATHERSTONE, RM .

BIOCHEMICAL PHARMACOLOGY, 1961, 7 (02) :88-&

[6] Soy phytochemicals decrease nonsmall cell lung cancer growth in female athymic mice [J].

Gallo, Daniela ;

Zannoni, Gian Franco ;

De Stefano, Ilaria ;

Mosca, Marco ;

Ferlini, Cristiano ;

Mantuano, Elisabetta ;

Scambia, Giovanni .

JOURNAL OF NUTRITION, 2008, 138 (07) :1360-1364

[7] Screening, optimization and validation of microwave-assisted extraction for the determination of persistent organochlorine pesticides [J].

Gfrerer, M ;

Lankmayr, E .

ANALYTICA CHIMICA ACTA, 2005, 533 (02) :203-211

[8] Inhibition of hippocampal function in mild cognitive impairment:: targeting the cholinergic hypothesis [J].

Grön, G ;

Brandenburg, I ;

Wunderlich, AP ;

Riepe, MW .

NEUROBIOLOGY OF AGING, 2006, 27 (01) :78-87

[9] Alzheimer disease is substantially preventable in the United States - review of risk factors, therapy, and the prospects for an expert software system [J].

Jansson, ET .

MEDICAL HYPOTHESES, 2005, 64 (05) :960-967

[10] Inhibitory Effect of Poncirus trifoliate on Acetylcholinesterase and Attenuating Activity against Trimethyltin-Induced Learning and Memory Impairment [J].

Kim, Jae Kyeom ;

Bae, Heyri ;

Kim, Mi-Jeong ;

Choi, Soo Jung ;

Cho, Hong Yon ;

Hwang, Han-Joon ;

Kim, Young Jun ;

Lim, Seung Taik ;

Kim, Eun Ki ;

Kim, Hye Kyung ;

Kim, Bok Yong ;

Shin, Dong-Hoon .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2009, 73 (05) :1105-1112

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