RETRACTED: Fluctuations of certain biochemical constituents and markers enzymes as a consequence of monocrotophos toxicity in the edible freshwater fish, Channa punctatus (Retracted article. See vol. 96, pg. 167, 2010)

被引：18

作者：

Agrahari, Shweta ^{[2
]}

Gopal, Krishna ^{[1
]}

机构：

[1] Indian Inst Toxicol Res, Lucknow 226001, Uttar Pradesh, India

[2] Univ Lucknow, Dept Zool, Lucknow 226007, Uttar Pradesh, India

来源：

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY | 2009年 / 94卷 / 01期

关键词：

Organophosphorus insecticide; Monocrotophos; Biochemical constituents; Marker enzymes; Channa punctatus; Tissues; ORGANOPHOSPHORUS INSECTICIDE; SUBLETHAL CONCENTRATIONS; PLASMA; TRANSAMINASES; ENDOSULFAN; EXPOSURE; GLYCOGEN;

D O I：

10.1016/j.pestbp.2009.02.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effect of exposure to two sublethal concentrations of an organophosphorus insecticide, monocrotophos (MCP) (0.96 and 1.86 mg l(-1)), on biochemical constituents and the activity of some marker enzymes such as acid phosphatase (ACP), alkaline phosphatase (ALP), aspartate aminotransferase (AAT), alanine aminotransferase (ALAT), and lactate dehydrogenase (LDH) in liver, kidney, gills, and Muscles of the edible freshwater fish, Channa punctatus, was studied after 30 days. The results revealed that there was overall decrease in total protein, carbohydrates, glycogen, free amino acid, and total lipid in the test samples compared to control. The AAT and ALAT activities were increased in kidney, where as liver, gills and muscles showed decrease. Increase in ACP and ALP activities were observed in gills, muscles and kidney, and reduction was observed in liver. Glycogen was depleted in liver, gills and kidney indicates of typical stress related response of the fish with pesticide. LDH activity was decreased in liver, muscles and kidney, but a significant increase in LDH activity in gills was observed. The results revealed that MCP induced impairment of metabolism in C punctatus and that the assayed enzymes can work as good biomarkers of organophosphorus contamination. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：5 / 9

页数：5

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