Unmet Need in Essential Thrombocythemia and Polycythemia Vera

被引：3
|
作者：
Kishtagari, Ashwin [1 ]
Gerds, Aaron T. [1 ]
机构：
[1] Cleveland Clin, Leukemia & Myeloid Disorders Program, Taussig Canc Inst, 9500 Euclid Ave,CA60, Cleveland, OH 44120 USA
来源：
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2021年 / 35卷 / 02期
关键词：
Myeloproliferative neoplasms; MPN; ET; PV; Bomedemstat; IFN-alpha; Idasanutlin; Givinostat;
D O I：
10.1016/j.hoc.2021.01.003
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Consensus guidelines have helped to standardize the care of patients with essential thrombocythemia and polycythemia vera, focusing on reducing the risk of thrombosis, mitigating symptoms, and avoiding therapies that may accelerate disease progression. However, many unmet needs still exist ranging from the roll of antiplatelet therapy in ET to medications that reduce disease progression. Retrospective studies suggest an improvement in myelofibrosis-free survival for treatment with interferons; new agents are looking to also enact disease modification. © 2021 Elsevier Inc.
引用
收藏
页码：295 / 303
页数：9
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