The effects of steamed ginger ethanolic extract on weight and body fat loss: a randomized, double-blind, placebo-controlled clinical trial

被引:28
|
作者
Park, Soo-Hyun [1 ,2 ]
Jung, Su-Jin [1 ]
Choi, Eun-Kyung [1 ]
Ha, Ki-Chan [3 ]
Baek, Hyang-Im [3 ]
Park, Yu-Kyung [3 ]
Han, Kap-Hoon [4 ,5 ]
Jeong, Soon-Yeon [5 ]
Oh, Jung-Hee [5 ]
Cha, Youn-Soo [2 ]
Park, Byung-Hyun [6 ]
Chae, Soo-Wan [1 ,7 ]
机构
[1] Chonbuk Natl Univ Hosp, Clin Trial Ctr Funct Foods, Jeonju Si, South Korea
[2] Chonbuk Natl Univ, Dept Food Sci & Human Nutr, Jeonju Si, South Korea
[3] Healthcare Claims & Management Inc, Jeonju Si, South Korea
[4] Woosuk Univ, Dept Pharmaceut Engn, Samnye Eup, Jeollabuk Do, South Korea
[5] Hlth Local Food Branding Agcy, Jeonbuk, South Korea
[6] Chonbuk Natl Univ, Med Sch, Dept Biochem, Jeonju Si, South Korea
[7] Chonbuk Natl Univ, Med Sch, Dept Pharmacol, Jeonju Si, South Korea
关键词
Steamed ginger ethanolic extract; 6-Shogaol; Body fat; Weight; Clinical trial; ANTIOXIDANT ACTIVITY; METABOLIC SYNDROME; ABDOMINAL OBESITY; MASS INDEX; DIET; METAANALYSIS; DISPARITIES; OVERWEIGHT; STABILITY; SHOGAOLS;
D O I
10.1007/s10068-019-00649-x
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Steamed ginger ethanolic extract (SGE) is a product with a high 6-shogaol contents and is thought to be more potent than other ginger products. We conducted a 12-week, randomized, double-blind, placebo-controlled clinical trial to determine the effects of SGE on weight and body fat loss. Eighty healthy obese participants were recruited and randomly divided into the SGE and placebo groups. The outcome measures comprised indicators of efficacy (body weight, body mass index, body composition, and blood markers) and safety. Following the supplementation period, mean body weight, body mass index, and body fat level were significantly lower in the SGE group than in the placebo group. No clinically significant changes were observed for any safety parameter. These results suggest that SGE is a potent anti-obesity agent that does not cause significant side effects. Therefore, SGE supplementation combined with lifestyle modification could be effective in the management of body weight and fat mass.
引用
收藏
页码:265 / 273
页数:9
相关论文
共 50 条
  • [31] Effects of oxcarbazepine versus carbamazepine on tinnitus: A randomized double-blind placebo-controlled clinical trial
    Gerami, Hooshang
    Saberi, Alia
    Nemati, Shadman
    Kazemnejad, Ehsan
    Aghajanpour, Mohammad
    IRANIAN JOURNAL OF NEUROLOGY, 2012, 11 (03) : 106 - 110
  • [32] Effects of creatine supplementation on renal function: a randomized, double-blind, placebo-controlled clinical trial
    Bruno Gualano
    Carlos Ugrinowitsch
    Rafael Batista Novaes
    Guilherme Gianini Artioli
    Maria Heloisa Shimizu
    Antonio Carlos Seguro
    Roger Charles Harris
    Antonio Herbert Lancha
    European Journal of Applied Physiology, 2008, 103 : 33 - 40
  • [33] Prevention of bone loss in survivors of breast cancer: A randomized, double-blind, placebo-controlled clinical trial
    Greenspan, Susan L.
    Bhattacharya, Rajib K.
    Sereika, Susan M.
    Brufsky, Adam
    Vogel, Victor G.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (01): : 131 - 136
  • [34] Effects of adjunctive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: a randomized, double-blind, placebo-controlled trial
    Fleischhacker, W. Wolfgang
    Heikkinen, Martti E.
    Olie, Jean-Pierre
    Landsberg, Wally
    Dewaele, Patricia
    McQuade, Robert D.
    Loze, Jean-Yves
    Hennicken, Delphine
    Kerselaers, Wendy
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2010, 13 (08): : 1115 - 1125
  • [35] Double-blind placebo-controlled randomized clinical trial of ginger (Zingiber officinale Rosc.) in the prophylactic treatment of migraine
    Martins, Lais Bhering
    dos Santos Rodrigues, Ana Maria
    Monteze, Nayara Mussi
    Braga Tibaes, Jenneffer Rayane
    Alves Amaral, Matheus Henrique
    Gomez, Rodrigo Santiago
    Teixeira, Antonio Lucio
    Matos Ferreira, Adaliene Versiani
    CEPHALALGIA, 2020, 40 (01) : 88 - 95
  • [36] Effects of neoagarooligosaccharides on body fat and bowel movement indicators in overweight or obese adults: A randomized, double-blind, placebo-controlled trial
    Kim, Yeounhee
    Jung, Soyoung
    Cho, Seong Ah
    Lee, Je Hyeon
    Kim, Eun Joo
    Ko, Hye-Jeong
    Park, Yoo Kyoung
    JOURNAL OF FUNCTIONAL FOODS, 2024, 121
  • [37] Effects of Methylphenidate on Fatigue and Depression: A Randomized, Double-Blind, Placebo-Controlled Trial
    Kerr, Christopher W.
    Drake, Julie
    Milch, Robert A.
    Brazeau, Daniel A.
    Skretny, Judith A.
    Brazeau, Gayle A.
    Donnelly, James P.
    JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 2012, 43 (01) : 68 - 77
  • [38] Arterial effects of acupuncture in migraine: A randomized, double-blind, placebo-controlled trial
    Boutouyrie, P
    Laloux, B
    Corvisier, R
    Vulser, C
    Girard, A
    Laurent, S
    HYPERTENSION, 2005, 46 (04) : 897 - 897
  • [39] Marfan Sartan: a randomized, double-blind, placebo-controlled trial
    Milleron, Olivier
    Arnoult, Florence
    Ropers, Jacques
    Aegerter, Philippe
    Detaint, Delphine
    Delorme, Gabriel
    Attias, David
    Tubach, Florence
    Dupuis-Girod, Sophie
    Plauchu, Henry
    Barthelet, Martine
    Sassolas, Francois
    Pangaud, Nicolas
    Naudion, Sophie
    Thomas-Chabaneix, Julie
    Dulac, Yves
    Edouard, Thomas
    Wolf, Jean-Eric
    Faivre, Laurence
    Odent, Sylvie
    Basquin, Adeline
    Habib, Gilbert
    Collignon, Patrick
    Boileau, Catherine
    Jondeau, Guillaume
    EUROPEAN HEART JOURNAL, 2015, 36 (32) : 2160 - U37
  • [40] Daily intake of rosehip extract decreases abdominal visceral fat in preobese subjects: a randomized, double-blind, placebo-controlled clinical trial
    Nagatomo, Akifumi
    Nishida, Norihisa
    Fukuhara, Ikuo
    Noro, Akira
    Kozai, Yoshimichi
    Sato, Hisao
    Matsuura, Yoichi
    DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2015, 8 : 147 - 156