Analytical applications of MIPs in diagnostic assays: future perspectives

被引:85
作者
Bedwell, Thomas S. [1 ]
Whitcombe, Michael J. [1 ]
机构
[1] Univ Leicester, Dept Chem, Coll Sci & Engn, Leicester LE1 7RH, Leics, England
基金
英国生物技术与生命科学研究理事会;
关键词
Molecularly imprinted polymers; Molecularly imprinted sorbent assay; Immunoassay; Radioassay; Fluoroimmunoassay; BELISA; MOLECULARLY IMPRINTED POLYMER; LINKED-IMMUNOSORBENT-ASSAY; DISTILLATION-PRECIPITATION POLYMERIZATION; SOLID-PHASE EXTRACTION; SCIENCE-AND-TECHNOLOGY; ONE-POT SYNTHESIS; SELECTIVE RECOGNITION; PHOTONIC CRYSTALS; ANTIBODY MIMICS; BINDING ASSAYS;
D O I
10.1007/s00216-015-9137-9
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Many efforts have been made to produce artificial materials with biomimetic properties for applications in binding assays. Among these efforts, the technique of molecular imprinting has received much attention because of the high selectivity obtainable for molecules of interest, robustness of the produced polymers, simple and short synthesis, and excellent cost efficiency. In this review, progress in the field of molecularly imprinted sorbent assays is discussed-with a focus on work conducted from 2005 to date.
引用
收藏
页码:1735 / 1751
页数:17
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