Effects of recombinant human growth hormone on fat distribution in patients with human immunodeficiency virus-associated wasting

被引：16
作者：
Tai, VW
Schambelan, M
Algren, H
Shayevich, C
Mulligan, K
机构：
[1] San Francisco Gen Hosp, Div Endocrinol, San Francisco, CA 94110 USA
[2] Univ Calif San Francisco, Dept Med, San Francisco, CA USA
来源：
CLINICAL INFECTIOUS DISEASES | 2002年 / 35卷 / 10期
关键词：
D O I：
10.1086/343051
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In light of current interest in recombinant human growth hormone (GH) as a treatment for fat distribution abnormalities, we retrospectively evaluated regional changes in fat and lean body mass in a subset of subjects who participated in randomized, double-blind, placebo-controlled trials of GH for treatment of wasting. Treatment with a pharmacologic dose of GH (0.1 mg/kg/day) resulted in significant and sustained increases in lean body mass and losses of fat in both the trunk and appendicular regions.
引用
收藏
页码：1258 / 1262
页数：5
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