Non-IgE- or Mixed IgE/Non-IgE-Mediated Gastrointestinal Food Allergies in the First Years of Life: Old and New Tools for Diagnosis

被引：55

作者：

Calvani, Mauro ^{[1
]}

Anania, Caterina ^{[2
]}

Cuomo, Barbara ^{[3
]}

D'Auria, Enza ^{[4
]}

Decimo, Fabio ^{[5
]}

Indirli, Giovanni Cosimo ^{[6
]}

Marseglia, Gianluigi ^{[7
]}

Mastrorilli, Violetta ^{[8
]}

Sartorio, Marco Ugo Andrea ^{[4
]}

Santoro, Angelica ^{[9
]}

Veronelli, Elisabetta ^{[10
]}

机构：

[1] S Camillo Forlanini Hosp, Operat Unit Pediat, I-00152 Rome, Italy

[2] Sapienza Univ Rome, Dept Mother Child, Immunol & Allergol Unit, Urol Sci, I-00161 Rome, Italy

[3] Belcolle Hosp, Operat Complex Unit Pediat, I-00100 Viterbo, Italy

[4] Univ Milan, Vittore Buzzi Childrens Hosp, Dept Pediat, I-20154 Milan, Italy

[5] Univ Campania Luigi Vanvitelli, Dept Woman Child & Gen & Specialized Surg, I-80100 Naples, Italy

[6] Pediat Allergol & Immunol SIAIP Reg Puglia & Basi, I-73100 Lecce, Italy

[7] Univ Pavia, Pediat Clin, Policlin San Matteo, Pediat Dept, I-27100 Pavia, Italy

[8] Giovanni XXIII Hosp, Operat Complex Unit Pediat & Emergency, I-70056 Bari, Italy

[9] Univ Parma, Mother Child Dept, Pediat Clin, I-43121 Parma, Italy

[10] Garbagnate Milanese Hosp, ASST Rhodense, Pediat Dept, Food Allergy Comm,Italian Soc Pediat Allergy & Im, I-70056 Garbagnate Milanese, Italy

来源：

NUTRIENTS | 2021年 / 13卷 / 01期

关键词：

non-IgE gastrointestinal food allergy; eosinophilic gastrointestinal disorders; fecal biomarkers; IgG and IgG4; allergen-specific lymphocyte stimulation test; oral food challenge; atopy patch test; clinical score; endoscopy; INDUCED ENTEROCOLITIS SYNDROME; COWS MILK ALLERGY; ATOPY PATCH TEST; LYMPHOCYTE STIMULATION TEST; INFLAMMATORY-BOWEL-DISEASE; FECAL CALPROTECTIN; EOSINOPHILIC ESOPHAGITIS; SYMPTOM-SCORE; CLINICAL-FEATURES; PEDIATRIC GASTROENTEROLOGY;

D O I：

10.3390/nu13010226

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

non-IgE and mixed gastrointestinal food allergies present various specific, well-characterized clinical pictures such as food protein-induced allergic proctocolitis, food protein-induced enterocolitis and food protein-induced enteropathy syndrome as well as eosinophilic gastrointestinal disorders such as eosinophilic esophagitis, allergic eosinophilic gastroenteritis and eosinophilic colitis. The aim of this article is to provide an updated review of their different clinical presentations, to suggest a correct approach to their diagnosis and to discuss the usefulness of both old and new diagnostic tools, including fecal biomarkers, atopy patch tests, endoscopy, specific IgG and IgG4 testing, allergen-specific lymphocyte stimulation test (ALST) and clinical score (CoMiss).

引用

页码：1 / 31

页数：31

共 50 条

[41] Tolerance to baked and fermented cow's milk in children with IgE-mediated and non-IgE-mediated cow's milk allergy in patients under two years of age [J].

Uncuoglu, A. ;

Yologlu, N. ;

Simsek, I. E. ;

Uyan, Z. S. ;

Aydogan, M. .

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 2017, 45 (06) :560-566

[42] FPIES - an unusual non-IgE-mediated food allergy. Overview and case studies [J].

Schmidt, H. ;

Adelsberger, D. ;

Bode, S. .

ALLERGOLOGIE, 2024, 47 (10) :621-629

[43] Associations between functional constipation and non-IgE-mediated food allergy in infants and children [J].

Sissoko, N'bamori Dite Naba ;

Chen, Wenxin ;

Wang, Chenhui ;

Wu, Yanling ;

Zheng, Xinguo ;

Dong, Xueting ;

Li, Mei ;

Yang, Hui .

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 2023, 51 (03) :163-173

[44] Non-IgE Mediated Food Allergy [J].

Cianferoni, Antonella .

CURRENT PEDIATRIC REVIEWS, 2020, 16 (02) :95-105

[45] Tolerance to a new free amino acid-based formula in children with IgE or non-IgE-mediated cow's milk allergy: a randomized controlled clinical trial [J].

Canani, Roberto Berni ;

Nocerino, Rita ;

Leone, Ludovica ;

Di Costanzo, Margherita ;

Terrin, Gianluca ;

Passariello, Annalisa ;

Cosenza, Linda ;

Troncone, Riccardo .

BMC PEDIATRICS, 2013, 13

[46] Outcomes and factors associated with tolerance in infants with non-IgE-mediated cow's milk allergy with gastrointestinal manifestations [J].

Vasconcelos, Priscila da Silva Pereira ;

Andrade, Ana Laura Mendes Becker ;

Sandy, Natascha Silva ;

Barreto, Juliana Correa Campos ;

Gomez, Gabriela Souza ;

Riccetto, Adriana Gut Lopes ;

Lomazi, Elizete Aparecida ;

Bellomo-Brandao, Maria Angela .

JORNAL DE PEDIATRIA, 2024, 100 (01) :40-45

[47] Approach to the spectrum of infant non-IgE-mediated food allergy manifestations and physiologic infant behaviors [J].

Herman, Katherine ;

Jarvinen, Kirsi M. .

CURRENT PROBLEMS IN PEDIATRIC AND ADOLESCENT HEALTH CARE, 2025, 55 (01)

[48] Low efficacy of atopy patch test in predicting tolerance development in non-IgE-mediated cow's milk allergy [J].

Gonzaga, T. A. ;

Alves, P. A. ;

Cheik, M. F. A. ;

de Barros, C. P. ;

Rezende, E. R. M. A. ;

Segundo, G. R. S. .

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 2018, 46 (03) :241-246

[49] Long-lasting non-IgE-mediated gastrointestinal cow's milk allergy in infants with Down syndrome [J].

Wakiguchi, Hiroyuki ;

Hasegawa, Shunji ;

Kaneyasu, Hidenobu ;

Kajimoto, Madoka ;

Fujimoto, Yousuke ;

Hirano, Reiji ;

Katsura, Shunsaku ;

Matsumoto, Kenji ;

Ichiyama, Takashi ;

Ohga, Shouichi .

PEDIATRIC ALLERGY AND IMMUNOLOGY, 2015, 26 (08) :821-823

[50] Characterization of Upper Gastrointestinal Motility in Infants With Persistent Distress and Non-IgE-mediated Cow's Milk Protein Allergy [J].

Omari, Taher ;

Tobin, Jacinta M. ;

McCall, Lisa ;

Savage, Karina ;

Ferris, Lara ;

Hammond, Paul ;

Kritas, Stamatiki ;

Quinn, Patrick ;

Abu-Assi, Rammy ;

Moore, David ;

Davidson, Geoffrey ;

Gold, Michael ;

Heine, Ralf G. .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2020, 70 (04) :489-496

← 1 2 3 4 5 →