MRI and characterization of atherosclerotic plaque - Emerging applications and molecular Imaging

被引:100
作者
Choudhury, RP
Fuster, V
Badimon, JJ
Fisher, EA
Fayad, ZA
机构
[1] CUNY Mt Sinai Sch Med, Zena & Michael A Wiener Cardiovasc Inst, New York, NY 10029 USA
[2] Univ Oxford, John Radcliffe Hosp, Dept Cardiovasc Med, Oxford OX3 9DU, England
关键词
MRI; atherosclerosis; plaque; molecular imaging; mice;
D O I
10.1161/01.ATV.0000019735.54479.2F
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Noninvasive high-resolution magnetic resonance has the potential to image atherosclerotic plaque and to determine its composition and microanatomy. This review summarizes the rationale for plaque imaging and describes the characteristics of plaque by use of existing MRI techniques. The use of MRI in human disease and in animal models, particularly in rabbits and mice, is presented. Present and future applications of MRI, including real-time vascular intervention, new contrast agents, and molecular imaging, are also discussed.
引用
收藏
页码:1065 / 1074
页数:10
相关论文
共 50 条
[21]   Imaging Atherosclerotic Plaque Calcification: Translating Biology [J].
Bailey, Grant ;
Meadows, Judith ;
Morrison, Alan R. .
CURRENT ATHEROSCLEROSIS REPORTS, 2016, 18 (08)
[22]   Characterization of coronary atherosclerotic plaque using multicontrast MRI acquired under simulated in vivo conditions [J].
Sun, Binjian ;
Giddens, Don P. ;
Long, Robert, Jr. ;
Taylor, W. Robert ;
Weiss, Diana ;
Joseph, Giji ;
Vega, David ;
Oshinski, John N. .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2006, 24 (04) :833-841
[23]   Imaging Atherosclerotic Plaque Calcification: Translating Biology [J].
Grant Bailey ;
Judith Meadows ;
Alan R. Morrison .
Current Atherosclerosis Reports, 2016, 18
[24]   Progress in atherosclerotic plaque imaging [J].
Soloperto, Giulia ;
Casciaro, Sergio .
WORLD JOURNAL OF RADIOLOGY, 2012, 4 (08) :353-371
[25]   Progress in atherosclerotic plaque imaging [J].
Giulia Soloperto ;
Sergio Casciaro .
World Journal of Radiology, 2012, (08) :353-371
[26]   State of the art: High resolution MR imaging of carotid atherosclerotic plaque [J].
Boussel, L. ;
Saloner, D. ;
Gamondes, D. ;
Serfaty, J. M. ;
Canet-Soulas, E. ;
Nighoghossian, N. ;
Douek, P. .
JOURNAL DE RADIOLOGIE, 2010, 91 (02) :185-194
[27]   Ultrasound Tissue Characterization of Vulnerable Atherosclerotic Plaque [J].
Picano, Eugenio ;
Paterni, Marco .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 16 (05) :10121-10133
[28]   Recent developments and new perspectives on imaging of atherosclerotic plaque: role of anatomical, cellular and molecular MRI Part I and II [J].
Boekhorst, Bernard C. M. Te ;
Cramer, Maarten J. ;
Pasterkamp, Gerard ;
van Echteld, Cees J. A. ;
Doevendans, Pieter A. F. M. .
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, 2010, 26 (04) :433-445
[29]   Molecular MRI of murine atherosclerotic plaque targeting NGAL: a protein associated with unstable human plaque characteristics [J].
Boekhorst, Bernard C. Te ;
Bovens, Sandra M. ;
Hellings, Willem E. ;
van der Kraak, Petra H. ;
de Kolk, Kees W. van ;
Vink, Aryan ;
Moll, Frans L. ;
van Oosterhout, Matthijs F. ;
de Vries, Jean P. ;
Doevendans, Pieter A. ;
Goumans, Marie-Jose ;
de Kleijn, Dominique P. ;
van Echteld, Cees J. ;
Pasterkamp, Gerard ;
Sluijter, Joost P. .
CARDIOVASCULAR RESEARCH, 2011, 89 (03) :680-688
[30]   In vivo Detection of Vulnerable Atherosclerotic Plaque by MRI in a Rabbit Model [J].
Phinikaridou, Alkystis ;
Ruberg, Frederick L. ;
Hallock, Kevin J. ;
Qiao, Ye ;
Hua, Ning ;
Viereck, Jason ;
Hamilton, James A. .
CIRCULATION-CARDIOVASCULAR IMAGING, 2010, 3 (03) :323-U155