MRI and characterization of atherosclerotic plaque - Emerging applications and molecular Imaging

被引：100

作者：

Choudhury, RP

Fuster, V

Badimon, JJ

Fisher, EA

Fayad, ZA

机构：

[1] CUNY Mt Sinai Sch Med, Zena & Michael A Wiener Cardiovasc Inst, New York, NY 10029 USA

[2] Univ Oxford, John Radcliffe Hosp, Dept Cardiovasc Med, Oxford OX3 9DU, England

来源：

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY | 2002年 / 22卷 / 07期

关键词：

MRI; atherosclerosis; plaque; molecular imaging; mice;

D O I：

10.1161/01.ATV.0000019735.54479.2F

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Noninvasive high-resolution magnetic resonance has the potential to image atherosclerotic plaque and to determine its composition and microanatomy. This review summarizes the rationale for plaque imaging and describes the characteristics of plaque by use of existing MRI techniques. The use of MRI in human disease and in animal models, particularly in rabbits and mice, is presented. Present and future applications of MRI, including real-time vascular intervention, new contrast agents, and molecular imaging, are also discussed.

引用

页码：1065 / 1074

页数：10

共 146 条

[1] Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma - A potential mechanism of lesion stabilization [J].