The uses of genome-wide yeast mutant collections

被引：72
|
作者：
Scherens, B
Goffeau, A
机构：
[1] Catholic Univ Louvain, Inst Sci Vie, B-1348 Louvain, Belgium
[2] Inst Rech Microbiol JM Wiame, B-1070 Brussels, Belgium
来源：
GENOME BIOLOGY | 2004年 / 5卷 / 07期
关键词：
D O I：
10.1186/gb-2004-5-7-229
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
We assess five years of usage of the major genome-wide collections of mutants from Saccharomyces cerevisiae: single deletion mutants, double mutants conferring 'synthetic' lethality and the 'TRIPLES' collection of mutants obtained by random transposon insertion. Over 100 experimental conditions have been tested and more than 5,000 novel phenotypic traits have been assigned to yeast genes using these collections.
引用
收藏
页数：8
相关论文
共 50 条
  • [1] The uses of genome-wide yeast mutant collections
    Bart Scherens
    Andre Goffeau
    Genome Biology, 5
  • [2] Genome-wide mutant collections: toolboxes for functional genomics
    Coelho, PSR
    Kumar, A
    Snyder, M
    CURRENT OPINION IN MICROBIOLOGY, 2000, 3 (03) : 309 - 315
  • [3] Genome-wide oscillation of transcription in yeast
    Reinke, H
    Gatfield, D
    TRENDS IN BIOCHEMICAL SCIENCES, 2006, 31 (04) : 189 - 191
  • [4] GENOME-WIDE MAPPING OF NUCLEOSOMES IN YEAST
    Rando, Oliver J.
    METHODS IN ENZYMOLOGY, VOL 470: GUIDE TO YEAST GENETICS:: FUNCTIONAL GENOMICS, PROTEOMICS, AND OTHER SYSTEMS ANALYSIS, 2ND EDITION, 2010, 470 : 105 - 118
  • [5] Genome-wide analysis of aging in yeast
    Kennedy, B
    Fields, S
    Kaeberlein, M
    Kirkland, K
    GERONTOLOGIST, 2004, 44 : 30 - 30
  • [6] PhylomeDB: a database for genome-wide collections of gene phylogenies
    Huerta-Cepas, Jaime
    Bueno, Anibal
    Dopazo, Joaquin
    Gabaldon, Toni
    NUCLEIC ACIDS RESEARCH, 2008, 36 : D491 - D496
  • [7] Genome-wide patterns of histone modifications in yeast
    Millar, Catherine B.
    Grunstein, Michael
    NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2006, 7 (09) : 657 - 666
  • [8] Genome-wide patterns of histone modifications in yeast
    Catherine B. Millar
    Michael Grunstein
    Nature Reviews Molecular Cell Biology, 2006, 7 : 657 - 666
  • [9] Yeast phenomics on a genome-wide scale.
    Warringer, J
    Ericson, E
    Fernandez, L
    Nerman, O
    Blomberg, A
    YEAST, 2003, 20 : S338 - S338
  • [10] Yeast ferments genome-wide functional analyses
    Goffeau, A
    Phillippsen, P
    Botstein, D
    NATURE GENETICS, 1996, 14 (01) : 1 - 2
12345