Cross-presentation by human dendritic cell subsets

被引：39

作者：

Segura, Elodie ^{[1
,2
]}

Amigorena, Sebastian ^{[1
,2
]}

机构：

[1] INSERM, U932, F-75005 Paris, France

[2] Inst Curie, Sect Rech, F-75005 Paris, France

来源：

IMMUNOLOGY LETTERS | 2014年 / 158卷 / 1-2期

基金：

欧洲研究理事会;

关键词：

Dendritic cells; Cross-presentation; CD8+T cells; Vaccination; HUMAN LANGERHANS CELLS; CD8(+) T-CELLS; HUMAN BLOOD; STEADY-STATE; ANTIGEN CROSSPRESENTATION; VIRAL-ANTIGENS; ACTIVATION; EXPRESSION; RESIDENT; SPLEEN;

D O I：

10.1016/j.imlet.2013.12.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Dendritic cells (DCs) are a heterogeneous population of professional antigen-presenting cells. Several murine DC subsets differ in their phenotype and functional properties, in particular in their ability to cross-present antigens (i.e. to present exogenous antigens on their MHC class I molecules). In humans, distinct DC subpopulations have also been identified but whether some human DC subsets are also specialized at cross-presentation remains debated. Here we review the DC subsets that have been identified in humans and we discuss recent work that addresses their ability to cross-present antigens and their efficiency for CD8(+) T cells activation. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：73 / 78

页数：6

共 71 条

[21] Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells [J].

Flinsenberg, Thijs W. H. ;

Compeer, Ewoud B. ;

Koning, Dan ;

Klein, Mark ;

Amelung, Femke J. ;

van Baarle, Debbie ;

Boelens, Jaap Jan ;

Boes, Marianne .

BLOOD, 2012, 120 (26) :5163-5172

[22] Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8α+ dendritic cells [J].

Franz Poulin, Lionel ;

Salio, Mariolina ;

Griessinger, Emmanuel ;

Anjos-Afonso, Fernando ;

Craciun, Ligia ;

Chen, Ji-Li ;

Keller, Anna M. ;

Joffre, Olivier ;

Zelenay, Santiago ;

Nye, Emma ;

Le Moine, Alain ;

Faure, Florence ;

Donckier, Vincent ;

Sancho, David ;

Cerundolo, Vincenzo ;

Bonnet, Dominique ;

Reis e Sousa, Caetano .

JOURNAL OF EXPERIMENTAL MEDICINE, 2010, 207 (06) :1261-1271

[23] Mobilizing monocytes to cross-present circulating viral antigen in chronic infection [J].

Gehring, Adam J. ;

Haniffa, Muzlifah ;

Kennedy, Patrick T. ;

Ho, Zi Zong ;

Boni, Carolina ;

Shin, Amanda ;

Banu, Nasirah ;

Chia, Adeline ;

Lim, Seng Gee ;

Ferrari, Carlo ;

Ginhoux, Florent ;

Bertoletti, Antonio .

JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (09) :3766-3776

[24] Ontogeny and homeostasis of Langerhans cells [J].

Ginhoux, Florent ;

Merad, Miriam .

IMMUNOLOGY AND CELL BIOLOGY, 2010, 88 (04) :387-392

[25] The origin and development of nonlymphoid tissue CD103+ DCs [J].

Ginhoux, Florent ;

Liu, Kang ;

Helft, Julie ;

Bogunovic, Milena ;

Greter, Melanie ;

Hashimoto, Daigo ;

Price, Jeremy ;

Yin, Na ;

Bromberg, Jonathan ;

Lira, Sergio A. ;

Stanley, E. Richard ;

Nussenzweig, Michel ;

Merad, Miriam .

JOURNAL OF EXPERIMENTAL MEDICINE, 2009, 206 (13) :3115-3130

[26] Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells [J].

Giodini, Alessandra ;

Cresswell, Peter .

EMBO JOURNAL, 2008, 27 (01) :201-211

[27] IRF8 Mutations and Human Dendritic-Cell Immunodeficiency [J].

Hambleton, Sophie ;

Salem, Sandra ;

Bustamante, Jacinta ;

Bigley, Venetia ;

Boisson-Dupuis, Stephanie ;

Azevedo, Joana ;

Fortin, Anny ;

Haniffa, Muzlifah ;

Ceron-Gutierrez, Lourdes ;

Bacon, Chris M. ;

Menon, Geetha ;

Trouillet, Celine ;

McDonald, David ;

Carey, Peter ;

Ginhoux, Florent ;

Alsina, Laia ;

Zumwalt, Timothy J. ;

Kong, Xiao-Fei ;

Kumararatne, Dinakantha ;

Butler, Karina ;

Hubeau, Marjorie ;

Feinberg, Jacqueline ;

Al-Muhsen, Saleh ;

Cant, Andrew ;

Abel, Laurent ;

Chaussabel, Damien ;

Doffinger, Rainer ;

Talesnik, Eduardo ;

Grumach, Anete ;

Duarte, Alberto ;

Abarca, Katia ;

Moraes-Vasconcelos, Dewton ;

Burk, David ;

Berghuis, Albert ;

Geissmann, Frederic ;

Collin, Matthew ;

Casanova, Jean-Laurent ;

Gros, Philippe .

NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (02) :127-138

[28] Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells [J].

Haniffa, Muzlifah ;

Shin, Amanda ;

Bigley, Venetia ;

McGovern, Naomi ;

Teo, Pearline ;

See, Peter ;

Wasan, Pavandip Singh ;

Wang, Xiao-Nong ;

Malinarich, Frano ;

Malleret, Benoit ;

Larbi, Anis ;

Tan, Pearlie ;

Zhao, Helen ;

Poidinger, Michael ;

Pagan, Sarah ;

Cookson, Sharon ;

Dickinson, Rachel ;

Dimmick, Ian ;

Jarrett, Ruth F. ;

Renia, Laurent ;

Tam, John ;

Song, Colin ;

Connolly, John ;

Chan, Jerry K. Y. ;

Gehring, Adam ;

Bertoletti, Antonio ;

Collin, Matthew ;

Ginhoux, Florent .

IMMUNITY, 2012, 37 (01) :60-73

[29] Antigen crosspresentation by human plasmacytoid dendritic cells [J].

Hoeffel, Guillaume ;

Ripoche, Anne-Claire ;

Matheoud, Diana ;

Nascimbeni, Michelina ;

Escriou, Nicolas ;

Lebon, Pierre ;

Heshmati, Farhad ;

Guillet, Jean-Gerard ;

Gannage, Monique ;

Caillat-Zucman, Sophie ;

Casartelli, Nicoletta ;

Schwartz, Olivier ;

De la Salle, Henri ;

Hanau, Daniel ;

Hosmalin, Anne ;

Maranon, Concepcion .

IMMUNITY, 2007, 27 (03) :481-492

[30] CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes [J].

Huysamen, Cristal ;

Willment, Janet A. ;

Dennehy, Kevin M. ;

Brown, Gordon D. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (24) :16693-16701

← 1 2 3 4 5 6 7 8 →