Methicillin-resistant Staphylococcus aureus carrying the new mecC gene-a meta-analysis

被引:27
作者
Diaz, Raquel [1 ]
Ramalheira, Elmano [2 ]
Afreixo, Vera [3 ]
Gago, Bruno [4 ]
机构
[1] Univ Aveiro, Inst Res Biomed iBiMED, Dept Hlth Sci, Hlth Sci Program, P-3810193 Aveiro, Portugal
[2] Univ Aveiro, Ctr Hosp Baixo Vouga, Dept Hlth Sci, Dept Med Microbiol, Av Artur Ravara, P-3814501 Aveiro, Portugal
[3] Univ Aveiro, Inst Biomed iBiMED, Dept Math, Hlth Sci Program, P-3810193 Aveiro, Portugal
[4] Univ Aveiro, Inst Biomed iBiMED, Dept Hlth Sci, Hlth Sci Program, P-3810193 Aveiro, Portugal
关键词
mecC gene; Staphylococcus aureus; Prevalence; CASSETTE CHROMOSOME MEC; MOLECULAR EPIDEMIOLOGY; BOVINE MASTITIS; HARBORING MECC; HOMOLOG; MRSA; PREVALENCE; LIVESTOCK; SAMPLES; DIVERSITY;
D O I
10.1016/j.diagmicrobio.2015.10.014
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
In 2011, a new mecA gene homolog, named mecC gene, was found in isolates from both humans and animals. The discovery of methicillin-resistant Staphylococcus aureus (MRSA) carrying the mecC gene has caused speculations about the origin, epidemiology, and impact of these isolates. The objective of this work is to perform a meta analysis on the prevalence of mecC MRSA, based on previously published results. Meta-analysis showed that the overall pooled prevalence is 0.009% (95% confidence interval = 0.05-0.013) and that there was evidence of heterogeneity (P < 0.01,12 = 97%). In conclusion, the very low reported prevalence provides an important baseline to monitor the epidemiology of this emerging form of MRSA. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:135 / 140
页数:6
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