Why Do We Feel Sick When Infected-Can Altruism Play a Role?

被引：72

作者：

Shakhar, Keren ^{[1
]}

Shakhar, Guy ^{[2
]}

机构：

[1] Coll Management Acad Studies, Dept Psychol, Rishon Leziyyon, Israel

[2] Weizmann Inst Sci, Dept Immunol, IL-76100 Rehovot, Israel

来源：

PLOS BIOLOGY | 2015年 / 13卷 / 10期

关键词：

IMMUNE-SYSTEM ACTIVATION; GENETIC RELATEDNESS; BACTERIAL LIPOPOLYSACCHARIDE; DEFENSE STRATEGY; SOCIAL-BEHAVIOR; HOST-DEFENSE; DISEASE; FEVER; IRON; COMMUNICATION;

D O I：

10.1371/journal.pbio.1002276

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

When we contract an infection, we typically feel sick and behave accordingly. Symptoms of sickness behavior (SB) include anorexia, hypersomnia, depression, and reduced social interactions. SB affects species spanning from arthropods to vertebrates, is triggered non-specifically by viruses, bacteria, and parasites, and is orchestrated by a complex network of cytokines and neuroendocrine pathways; clearly, it has been naturally selected. Nonetheless, SB seems evolutionarily costly: it promotes starvation and predation and reduces reproductive opportunities. How could SB persist? Former explanations focused on individual fitness, invoking improved resistance to pathogens. Could prevention of disease transmission, propagating in populations through kin selection, also contribute to SB?

引用

页码：1 / 15

页数：15

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