Carbon quantum dot-gold nanocluster nanosatellite for ratiometric fluorescence probe and imaging for hydrogen peroxide in living cells

被引：93
作者：
Li, Zenghe [1 ]
Guo, Song [1 ]
Yuan, Zhiqin [1 ]
Lu, Chao [1 ]
机构：
[1] Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China
来源：
SENSORS AND ACTUATORS B-CHEMICAL | 2017年 / 241卷
关键词：
Carbon quantum dots; Gold nanoclusters; Ratiometric fluorescence; Hydrogen peroxide; SENSITIVE DETECTION; METAL NANOCLUSTERS; REACTIVE OXYGEN; INDUCED EMISSION; AU NANOCLUSTERS; GREEN SYNTHESIS; LIVE CELLS; IN-VITRO; NANODOTS; NITROGEN;
D O I：
10.1016/j.snb.2016.10.134
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Developing probes for sensitive H2O2 detection is critical for understanding its related physiological and pathological processes. In this study, novel carbon quantum dot-gold nano cluster (CQD-AuNC) nanosatellite with high fluorescence energy transfer efficiency (-40%) and dual-emission fluorescent properties have been exploited for fluorescence ratiometric sensing of H2O2. The sensing mechanism was based on the fact that H2O2 can quench the red emission of AuNCs. Under the optimal conditions, the CQD-AuNC nanosatellite probe was sensitive to H2O2 in the range from 5.0 nM to 80 nM with a limit of detection of 2.9 nM. The practicality of the proposed CQD-AuNC nanosatellite probe was validated by imaging H2O2 in living cells. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：821 / 827
页数：7
相关论文
共 50 条
[1]   Imaging Fluorescence Fluctuation Spectroscopy: New Tools for Quantitative Bioimaging [J].
Bag, Nirmalya ;
Wohland, Thorsten .
ANNUAL REVIEW OF PHYSICAL CHEMISTRY, VOL 65, 2014, 65 :225-248
[2]   Quenching of photoluminescence in conjugates of quantum dots and single-walled carbon nanotube [J].
Biju, Vasudevanpillai ;
Itoh, Tamitake ;
Baba, Yoshinobu ;
Ishikawa, Mitsuru .
JOURNAL OF PHYSICAL CHEMISTRY B, 2006, 110 (51) :26068-26074
[3]   Fluorescent Gold Nanoclusters: Recent Advances in Sensing and Imaging [J].
Chen, Li-Yi ;
Wang, Chia-Wei ;
Yuan, Zhiqin ;
Chang, Huan-Tsung .
ANALYTICAL CHEMISTRY, 2015, 87 (01) :216-229
[4]   Photoluminescent organosilane-functionalized carbon dots as temperature probes [J].
Chen, Po-Cheng ;
Chen, Ya-Na ;
Hsu, Pin-Che ;
Shih, Chung-Chien ;
Chang, Huan-Tsung .
CHEMICAL COMMUNICATIONS, 2013, 49 (16) :1639-1641
[5]   A Dual-Emission Fluorescent Nanocomplex of Gold-Cluster-Decorated Silica Particles for Live Cell Imaging of Highly Reactive Oxygen Species [J].
Chen, Tingting ;
Hu, Yihui ;
Cen, Yao ;
Chu, Xia ;
Lu, Yi .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (31) :11595-11602
[6]   Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species [J].
Chen, Xiaoqiang ;
Tian, Xizhe ;
Shin, Injae ;
Yoon, Juyoung .
CHEMICAL SOCIETY REVIEWS, 2011, 40 (09) :4783-4804
[7]   Synthesis and Unique Photoluminescence Properties of Nitrogen-Rich Quantum Dots and Their Applications [J].
Chen, Xiuxian ;
Jin, Qingqing ;
Wu, Lizhu ;
Tung, ChenHo ;
Tang, Xinjing .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (46) :12542-12547
[8]   Functionalized gold nanoclusters as fluorescent labels for immunoassays: Application to human serum immunoglobulin E determination [J].
Cruz Alonso, Maria ;
Trapiella-Alfonso, Laura ;
Costa Fernandez, Jose M. ;
Pereiro, Rosario ;
Sanz-Medel, Alfredo .
BIOSENSORS & BIOELECTRONICS, 2016, 77 :1055-1061
[9]   pH-Sensitive gold nanoclusters: preparation and analytical applications for urea, urease, and urease inhibitor detection [J].
Deng, Hao-Hua ;
Wu, Gang-Wei ;
Zou, Zhi-Qiang ;
Peng, Hua-Ping ;
Liu, Ai-Lin ;
Lin, Xin-Hua ;
Xia, Xing-Hua ;
Chen, Wei .
CHEMICAL COMMUNICATIONS, 2015, 51 (37) :7847-7850
[10]   Carbon-Based Dots Co-doped with Nitrogen and Sulfur for High Quantum Yield and Excitation-Independent Emission [J].
Dong, Yongqiang ;
Pang, Hongchang ;
Yang, Hong Bin ;
Guo, Chunxian ;
Shao, Jingwei ;
Chi, Yuwu ;
Li, Chang Ming ;
Yu, Ting .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (30) :7800-7804
12345