Two Novel Cu(II) and Zn(II)-based Coordination Polymers: Inhibition of Human Ovarian Cancer Cells

被引：0

作者：

Duan, Li ^{[1
]}

Yang, Haiting ^{[2
]}

Wang, Guan ^{[1
]}

机构：

[1] Heilongjiang Prov Hosp, Dept Obstet & Gynaecol, Nangang Campus, Harbin 150086, Heilongjiang, Peoples R China

[2] Heilongjiang Elect Power Hosp, Dept Ophthalmol, Harbin 150000, Heilongjiang, Peoples R China

来源：

LATIN AMERICAN JOURNAL OF PHARMACY | 2018年 / 37卷 / 02期

关键词：

coordination polymer; ovarian cancer; X-ray; METAL; COMPLEXES;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Two new Cu(II)-and Zn(II)-based coordination polymers, [Cu-2(bmip)(H2O)(4) (Br2BDC)center dot(Br2BDC)(H2O)(2)](n) [1, bmip = 1,3-bis(2-methylimidazolyl) propane, H2Br2BDC = tetrabro-moterephthalic acid] and [ZnCl(2)bmip](n) (2), have been successfully synthesized and structurally characterized by single crystal X-ray analysis. In addition, in vitro anticancer activities of compounds 1 and 2 on four human ovarian cancer cell lines (COC1, 3AO, SKOV3 and OVCAR3) was further determined.

引用

页码：313 / 316

页数：4

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