Two Novel Cu(II) and Zn(II)-based Coordination Polymers: Inhibition of Human Ovarian Cancer Cells

被引:0
作者
Duan, Li [1 ]
Yang, Haiting [2 ]
Wang, Guan [1 ]
机构
[1] Heilongjiang Prov Hosp, Dept Obstet & Gynaecol, Nangang Campus, Harbin 150086, Heilongjiang, Peoples R China
[2] Heilongjiang Elect Power Hosp, Dept Ophthalmol, Harbin 150000, Heilongjiang, Peoples R China
来源
LATIN AMERICAN JOURNAL OF PHARMACY | 2018年 / 37卷 / 02期
关键词
coordination polymer; ovarian cancer; X-ray; METAL; COMPLEXES;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Two new Cu(II)-and Zn(II)-based coordination polymers, [Cu-2(bmip)(H2O)(4) (Br2BDC)center dot(Br2BDC)(H2O)(2)](n) [1, bmip = 1,3-bis(2-methylimidazolyl) propane, H2Br2BDC = tetrabro-moterephthalic acid] and [ZnCl(2)bmip](n) (2), have been successfully synthesized and structurally characterized by single crystal X-ray analysis. In addition, in vitro anticancer activities of compounds 1 and 2 on four human ovarian cancer cell lines (COC1, 3AO, SKOV3 and OVCAR3) was further determined.
引用
收藏
页码:313 / 316
页数:4
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