Medium-Throughput Characterization of Engineered AAV Transduction Properties in NHP Retina

被引：0

作者：

Sengel, Cem ^{[1
]}

Shanehsazzadeh, Amir ^{[1
]}

Wec, Anna ^{[1
]}

Reardon, Chris ^{[1
]}

Locane, Elina ^{[1
]}

Lykken, Erik ^{[1
]}

Damani, Farhan ^{[1
]}

Levitin, Hanna Mendes ^{[1
]}

Turunen, Heikki ^{[1
]}

Kuchwara, Helene ^{[1
]}

Chen, Ina ^{[1
]}

Yu, Jennifer ^{[1
]}

Lin, Kathy ^{[1
]}

Wheelock, Lauren ^{[1
]}

Nagabhushana, Nishith ^{[1
]}

McDonel, Patrick ^{[1
]}

Badkundri, Rohil ^{[1
]}

Wolock, Sam ^{[1
]}

Abesteh, Shireen ^{[1
]}

Malina, Stephen ^{[1
]}

Lapan, Sylvain ^{[1
]}

机构：

[1] Dyno Therapeut, Watertown, MA USA

来源：

MOLECULAR THERAPY | 2022年 / 30卷 / 04期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

936

引用

页码：441 / 441

页数：1

共 11 条

[1] Engineered AAV Capsids for Efficient Muscle Transduction in NHP
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Wu, Zhenhua
Pang, Xiaodong
Li, Shaoyong
Li, Zhongwan
Zhang, Runyuan
Li, Guanlin
Lan, Xing
Jiang, Yuling
Zheng, Yanyan
Wan, Changpeng
Ye, Guo-jie
MOLECULAR THERAPY, 2024, 32 (04) : 267 - 267
[2] AI-Aided AAV Capsids Design for Efficient Retina Transduction in NHP
Chen, Shuyuan
Pang, Xiaodong
Wan, Changpeng
Li, Zhongwan
Wu, Weiwei
Zhang, Runyuan
Lan, Xing
Li, Guanlin
Wu, Zhenhua
Li, Shaoyong
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MOLECULAR THERAPY, 2024, 32 (04) : 682 - 682
[3] Characterization of Engineered AAV Capsids for Improved Transduction Efficiency through Rational Design
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[4] Characterization of engineered AAV capsids in the retina of mice and in two novel human retina ex vivo models
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Strobel, B.
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Sun, M.
Oti, M.
Alanis-Lobato, G.
Loskill, P.
Kuehn, M. H.
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Maier, U.
Michelfelder, S.
HUMAN GENE THERAPY, 2022, 33 (23-24) : A27 - A28
[5] High Throughput LCMS Characterization to Promote Chemically Engineered AAV Capsids Development
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Yamada, Kentaro
Zhang, Junping
Frabutt, Dylan
Mulcrone, Patrick
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[6] Performance of Mouse Neural Stem Cells as a Screening Reagent: Characterization of PAC1 Activity in Medium-Throughput Functional Assays
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Langmead, Christopher J.
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[7] Identification and Characterization of STAC-BBB, an Engineered AAV Capsid That Exhibits Widespread Transduction of the Central Nervous System in Cynomolgus Macaques
Tiffany, Matthew R.
Frias, Stephanye
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Nanjaraj, Ankitha
Darst, Russell
Wist, Stephen
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[8] Functional Characterization of AAVHSC Compared to AAV Serotypes: Activation of Cellular Pathways In Vitro and In Vivo Transduction Properties
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MOLECULAR THERAPY, 2021, 29 (04) : 152 - 153
[9] Fast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS
Lam, Anh K.
Zhang, Junping
Frabutt, Dylan
Mulcrone, Patrick L.
Li, Lei
Zeng, Lifan
Herzog, Roland W.
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MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2022, 27 : 185 - 194
[10] A medium-throughput screening assay to determine catalytic activities of oxygen-consuming enzymes: a new tool for functional characterization of cytochrome P450 and other oxygenases
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PLANT JOURNAL, 2007, 51 (02): : 331 - 340

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