Bacterial Pneumonia in Patients with Cancer Novel Risk Factors and Management

被引:62
作者
Wong, Justin L. [1 ]
Evans, Scott E. [2 ]
机构
[1] Univ Texas Houston, Hlth Sci Ctr, Dept Pulm Crit Care & Sleep Med, Div Internal Med, 6431 Fannin St,MSB 1-434, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Pulm Med, Div Internal Med, 1515 Holcombe Blvd,Unit 1100, Houston, TX 77030 USA
关键词
Bacterial pneumonia; Cancer; Neutropenia; Hematologic malignancy; Stem cell transplant; Immunocompromised host pneumonia; STEM-CELL TRANSPLANTATION; INVASIVE PNEUMOCOCCAL DISEASE; COMMUNITY-ACQUIRED PNEUMONIA; URINARY ANTIGEN TEST; STREPTOCOCCUS-PNEUMONIAE; HEMATOLOGIC MALIGNANCIES; ORAL MUCOSITIS; LUNG-CANCER; INFECTIOUS COMPLICATIONS; POSTOPERATIVE PNEUMONIA;
D O I
10.1016/j.ccm.2016.12.005
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Bacterial pneumonias exact unacceptable morbidity on patients with cancer. Although the risk is often most pronounced among patients with treatment-induced cytopenias, the numerous contributors to life-threatening pneumonias in cancer populations range from derangements of lung architecture and swallow function to complex immune defects associated with cytotoxic therapies and graft-versus-host disease. These structural and immunologic abnormalities often make the diagnosis of pneumonia challenging in patients with cancer and impact the composition and duration of therapy. This article addresses host factors that contribute to pneumonia susceptibility, summarizes diagnostic recommendations, and reviews current guidelines for management of bacterial pneumonia in patients with cancer.
引用
收藏
页码:263 / +
页数:16
相关论文
共 149 条
[41]  
Garcia Javier Barreda, 2013, Ann Am Thorac Soc, V10, P432, DOI 10.1513/AnnalsATS.201304-097OC
[42]   Lymphocyte recovery is impaired in patients with chronic lymphocytic leukemia and indolent non-Hodgkin lymphomas treated with bendamustine plus rituximab [J].
Garcia Munoz, Ricardo ;
Izquierdo-Gil, Araceli ;
Munoz, Aura ;
Roldan-Galiacho, Veronica ;
Rabasa, Pilar ;
Panizo, Carlos .
ANNALS OF HEMATOLOGY, 2014, 93 (11) :1879-1887
[43]   Patterns of infection and infection-related mortality in patients with steroid-refractory acute graft versus host disease [J].
Garcia-Cadenas, I. ;
Rivera, I. ;
Martino, R. ;
Esquirol, A. ;
Barba, P. ;
Novelli, S. ;
Orti, G. ;
Briones, J. ;
Brunet, S. ;
Valcarcel, D. ;
Sierra, J. .
BONE MARROW TRANSPLANTATION, 2017, 52 (01) :107-113
[44]   Pneumococcal pneumonia presenting with septic shock: host- and pathogen-related factors and outcomes [J].
Garcia-Vidal, C. ;
Ardanuy, C. ;
Tubau, F. ;
Viasus, D. ;
Dorca, J. ;
Linares, J. ;
Gudiol, F. ;
Carratala, J. .
THORAX, 2010, 65 (01) :77-81
[45]   Inhaled aminoglycosides in cancer patients with ventilator-associated Gram-negative bacterial pneumonia: safety and feasibility in the era of escalating drug resistance [J].
Ghannam, D. E. ;
Rodriguez, G. H. ;
Raad, I. I. ;
Safdar, A. .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2009, 28 (03) :253-259
[46]   Utility of Flexible Bronchoscopy in the Evaluation of Pulmonary Infiltrates in the Hematopoietic Stem Cell Transplant Population - A Single Center Fourteen Year Experience [J].
Gilbert, Christopher R. ;
Lerner, Andrew ;
Baram, Michael ;
Awsare, Bharat K. .
ARCHIVOS DE BRONCONEUMOLOGIA, 2013, 49 (05) :189-195
[47]   Predicting pneumonia mortality using CURB-65, PSI, and patient characteristics in patients presenting to the emergency department of a comprehensive cancer center [J].
Gonzalez, Carmen ;
Johnson, Tami ;
Rolston, Kenneth ;
Merriman, Kelly ;
Warneke, Carla ;
Evans, Scott .
CANCER MEDICINE, 2014, 3 (04) :962-970
[48]  
Guinan John L, 2003, Oncology (Williston Park), V17, P415
[49]   Periodontal status and post-transplantation complications following intensive periodontal treatment in patients underwent allogenic hematopoietic stem cell transplantation conditioned with myeloablative regimen [J].
Gurgan, C. A. ;
Ozcan, M. ;
Karakus, O. ;
Zincircioglu, G. ;
Arat, M. ;
Soydan, E. ;
Topcuoglu, P. ;
Gurman, G. ;
Bostanci, H. S. .
INTERNATIONAL JOURNAL OF DENTAL HYGIENE, 2013, 11 (02) :84-90
[50]   Bronchopulmonary neuroendocrine tumors [J].
Gustafsson, Bjorn I. ;
Kidd, Mark ;
Chan, Anthony ;
Malfertheiner, Max V. ;
Modlin, Irvin M. .
CANCER, 2008, 113 (01) :5-21