Bacterial Pneumonia in Patients with Cancer Novel Risk Factors and Management

被引:62
作者
Wong, Justin L. [1 ]
Evans, Scott E. [2 ]
机构
[1] Univ Texas Houston, Hlth Sci Ctr, Dept Pulm Crit Care & Sleep Med, Div Internal Med, 6431 Fannin St,MSB 1-434, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Pulm Med, Div Internal Med, 1515 Holcombe Blvd,Unit 1100, Houston, TX 77030 USA
关键词
Bacterial pneumonia; Cancer; Neutropenia; Hematologic malignancy; Stem cell transplant; Immunocompromised host pneumonia; STEM-CELL TRANSPLANTATION; INVASIVE PNEUMOCOCCAL DISEASE; COMMUNITY-ACQUIRED PNEUMONIA; URINARY ANTIGEN TEST; STREPTOCOCCUS-PNEUMONIAE; HEMATOLOGIC MALIGNANCIES; ORAL MUCOSITIS; LUNG-CANCER; INFECTIOUS COMPLICATIONS; POSTOPERATIVE PNEUMONIA;
D O I
10.1016/j.ccm.2016.12.005
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Bacterial pneumonias exact unacceptable morbidity on patients with cancer. Although the risk is often most pronounced among patients with treatment-induced cytopenias, the numerous contributors to life-threatening pneumonias in cancer populations range from derangements of lung architecture and swallow function to complex immune defects associated with cytotoxic therapies and graft-versus-host disease. These structural and immunologic abnormalities often make the diagnosis of pneumonia challenging in patients with cancer and impact the composition and duration of therapy. This article addresses host factors that contribute to pneumonia susceptibility, summarizes diagnostic recommendations, and reviews current guidelines for management of bacterial pneumonia in patients with cancer.
引用
收藏
页码:263 / +
页数:16
相关论文
共 149 条
[1]   Multiplex quantitative PCR for detection of lower respiratory tract infection and meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis [J].
Abdeldaim, Guma M. K. ;
Stralin, Kristoffer ;
Korsgaard, Jens ;
Blomberg, Jonas ;
Welinder-Olsson, Christina ;
Herrmann, Bjorn .
BMC MICROBIOLOGY, 2010, 10
[2]   Pneumonia in allogeneic stem cell transplantation recipients: a multicenter prospective study [J].
Aguilar-Guisado, Manuela ;
Jimenez-Jambrina, Margarita ;
Espigado, Ildefonso ;
Rovira, Montserrat ;
Martino, Rodrigo ;
Oriol, Albert ;
Borrell, Nuria ;
Ruiz, Isabel ;
Martin-Davila, Pilar ;
de la Camara, Rafael ;
Salavert, Miquel ;
de la Torre, Julian ;
Miguel Cisneros, Jose .
CLINICAL TRANSPLANTATION, 2011, 25 (06) :E629-E638
[3]  
Al-Ansari Sali, 2015, Curr Oral Health Rep, V2, P202
[4]  
Aliberti S, 2009, INT J TUBERC LUNG D, V13, P1550
[5]   Microbial spectrum and antibiotic susceptibility profile of gram-positive aerobic bacteria isolated from cancer patients [J].
Ashour, Hossam M. ;
El-Sharif, Amany .
JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (36) :5763-5769
[6]   Diagnostic bronchoscopy in hematology and oncology patients with acute respiratory failure: Prospective multicenter data [J].
Azoulay, Elie ;
Mokart, Djamel ;
Rabbat, Antoine ;
Pene, Federic ;
Kouatchet, Achille ;
Bruneel, Fabrice ;
Vincent, Francois ;
Hamidfar, Rebecca ;
Moreau, Delphine ;
Mohammedi, Ismaeel ;
Epinette, Geraldine ;
Beduneau, Gaeetan ;
Castelain, Vincent ;
de Lassence, Arnaud ;
Gruson, Didier ;
Lemiale, Virginie ;
Renard, Benoit ;
Chevret, Sylvie ;
Schlemmer, Benoit .
CRITICAL CARE MEDICINE, 2008, 36 (01) :100-107
[7]   Role of pathogenic oral flora in postoperative pneumonia following brain surgery [J].
Bagyi, Kinga ;
Haczku, Angela ;
Marton, Ildiko ;
Szabo, Judit ;
Gaspar, Attila ;
Andrasi, Melinda ;
Varga, Imre ;
Toth, Judit ;
Klekner, Almos .
BMC INFECTIOUS DISEASES, 2009, 9
[8]  
Bartlett Jennifer A., 2008, V15, P147, DOI 10.1159/000136349
[9]   The response to vaccination against influenza A(H1N1) 2009, seasonal influenza and Streptococcus pneumoniae in adult outpatients with ongoing treatment for cancer with and without rituximab [J].
Berglund, Ake ;
Willen, Linda ;
Grodeberg, Lina ;
Skattum, Lillemor ;
Hagberg, Hans ;
Pauksens, Karlis .
ACTA ONCOLOGICA, 2014, 53 (09) :1212-1220
[10]   Clinical value of FDG PET in patients with fever of unknown origin and patients suspected of focal infection or inflammation [J].
Bleeker-Rovers, CP ;
de Kleijn, EMHA ;
Corstens, FHM ;
van der Meer, JWM ;
Oyen, WJG .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2004, 31 (01) :29-37