Synthesis and Characterization of New Schiff Bases Derived from N (1)-Substituted Isatin with Dithiooxamide and Their Co(II), Ni(II), Cu(II), Pd(II), and Pt(IV) Complexes

Three new Schiff bases of N-substituted isatin L-I, L-II, and L-III = Schiff base of N-acetylisatin, N-benzylisatin, and N-benzoylisatin, respectively, and their metal complexes C-1a,C-b = [Co-2(L-I)(2)Cl-3] Cl, C-2 = [Ni(L-I)(2)Cl-2]0.4BuOH, C-3 = [CuLICl(H2O)]Cl center dot 0.5BuOH, C-4 = [Pd(L-I)(2)Cl]Cl, C-5 = [Pt(L-1)(2)Cl-2]Cl-2 center dot 1.8EtOH center dot H2O, C-6a = [CoLIICl]Cl center dot 0.4H(2)O center dot 0.3DMSO, C-6b = [CoLIICl]Cl center dot 0.3H(2)O center dot 0.1BuOH, C-7 = [NiLIICl2], C-8 = [CuLII]Cl-2 center dot H2O, C-9 = [Pd(L-II)(2)]Cl-2, C-10 = [Pt(L-II)(2.5)Cl]Cl-3, C-11a = [Co(L-III)]C-12 center dot H2O, C-11b = [Co(L-III)] Cl-2 center dot 0.2H(2)O, and C-12 = [Ni(L-III)(2)]Cl-2, C-13 = [Ni(L-III)(2)]Cl-2 were reported. The complexes were characterized by elemental analyses, metal and chloride content, spectroscopic methods, magnetic moments, conductivity measurements, and thermal studies. Some of these compounds were tested as antibacterial and antifungal agents against Staphylococcus aureus, Proteus vulgaris, Candida albicans, and Aspergillus niger. Copyright (C) 2009 A. J. Abdul-Ghani and A. M. N. Khaleel.