A Major Saponin from Leaves Extract of Acer velutinum

被引：9

作者：

Glensk, Michal ^{[1
]}

Wlodarczyk, Maciej ^{[1
]}

Bassarello, Carla ^{[2
]}

Pizza, Cosimo ^{[2
]}

Stefanowicz, Piotr ^{[3
]}

Switalska, Marta ^{[4
]}

机构：

[1] Wroclaw Med Univ, Dept Pharmacognosy, PL-50140 Wroclaw, Poland

[2] Univ Salerno, Univ Ricercatore Biol Farmaceut, Dipartimento Sci Farmaceut, I-84084 Fisciano, Italy

[3] Univ Wroclaw, Fac Chem, PL-50383 Wroclaw, Poland

[4] Polish Acad Sci, Inst Immunol & Expt Therapy, Dept Expt Oncol, PL-53114 Wroclaw, Poland

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2009年 / 64卷 / 09期

关键词：

Acer velutinum (Boiss.); Aceraceae; Triterpenoid Saponin; Protoaescigenin; Cytotoxicity; TRITERPENOID SAPONINS; INJURY; ESTER;

D O I：

10.1515/znb-2009-0915

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A major triterpenoid saponin was isolated from the leaves extract of Acer velutinum. This compound was characterized as 21 beta,22 alpha-O-diangeloylprotoaescigenin 3-O-[beta-D-glucopyranosyl-(1 -> 2)][beta-D-glucopyranosyl-(1 -> 4)]-beta-D-glucuronopyranosyl acid. Its structure was elucidated by (1)H, gCOSY, ROESY, gHSQC, gHMBC NMR as well as ESI-MS experiments. Isolated saponin exhibited in vitro cytotoxicity against HL-60, B16-F0 and BALB/3T3 cell lines.

引用

页码：1081 / 1086

页数：6

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