Intramyocardial bone marrow stem cell treatment for myocardial regeneration

被引：2
作者：
Steinhoff, Gustav
Choi, Yeong-Hoon
Stamm, Christof
机构：
[1] Univ Rostock, Fak Med, Klin & Poliklin Herzchirurg, Dept Cardiac Surg, D-18057 Rostock, Germany
[2] German Heart Ctr Berlin, Berlin, Germany
来源：
EUROPEAN HEART JOURNAL SUPPLEMENTS | 2006年 / 8卷 / 0H期
关键词：
stem cells; angiogenesis; myogenesis; cardiac surgery; heart failure;
D O I：
10.1093/eurheartj/sul065
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Transplantation of stem cells has been shown by substantial experimental evidence as well as by initial clinical studies to improve cardiac function in patients with post-infarction myocardial injury. Both angiogenic and myogenic properties of bone-marrow-derived stem cells have been evidenced to be involved in its beneficial effect on heart function after transplantation into area of ischaemic injury. This paper summarizes the current knowledge on the mechanisms involved in regenerative potential of bone-marrow-derived stem cells, with special attention to the clinical experience with cell transplantation during cardiac surgery.
引用
收藏
页码：H32 / H39
页数：8
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