Preparation and Characterization of Holmium-2-Hydroxypropyl β-Cyclodextrin Inclusion Complex and Its Stability under Gamma Radiation

被引：0
|
作者：
Lopez-Gonzalez, H. [1 ]
Jimenez-Becerril, J. [1 ]
Bautista-Santiago, C. [1 ]
Rojas-Hernandez, A. [2 ]
机构：
[1] Inst Nacl Invest Nucl, Dept Quim, Direcc Invest Cient, Gerencia Ciencias Bas, Mexico City 11801, Mexico
[2] Univ Autonoma Metropolitana Iztapalapa, Dept Quim, Area Quim Analit, Mexico City 09340, Mexico
来源：
RADIOCHEMISTRY | 2022年 / 64卷 / 06期
关键词：
holmium; 2-hydroxypropyl beta-cyclodextrin; inclusion complex; stability; gamma radiation; HOLMIUM NITRATE; 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN; NANOPARTICLES; GEL;
D O I：
10.1134/S1066362222060133
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The holmium inclusion complex with 2-hydroxypropyl beta-cyclodextrin (Ho-2-HP-beta-CD) was prepared and characterized by X-ray diffraction, IR and Raman spectroscopy, and thermogravimetric analysis. The preparation process involves the reaction of a solution of Ho(NO3)(3)center dot 5H(2)O with an aqueous solution of the 2-hydroxypropyl beta-cyclodextrin (2-HP-beta-CD). The compound's stability under gamma radiation in the range from 1 to 10000 Gy was studied. Only UV spectrophotometry reveals changes in the Ho-2-HP-beta-CD inclusion complex at the highest gamma radiation dose used. The stability at low doses and high solubility make Ho-2-HP-beta-CD inclusion complex a compound of interest in the new applications of lanthanides as therapeutic and biomedical agents.
引用
收藏
页码：757 / 765
页数：9
相关论文
共 50 条
  • [21] Characterization of Quercetin/Hydroxypropyl-β-Cyclodextrin Inclusion Complex
    Yang, Li
    Yan, Qinghua
    Liu, Benguo
    Zhang, Yan
    Zhang, Jianwei
    Fu, Qiang
    ASIAN JOURNAL OF CHEMISTRY, 2012, 24 (07) : 3141 - 3144
  • [22] Characterization of lidocaine:hydroxypropyl-β-cyclodextrin inclusion complex
    Carolina Morales Moraes
    Priscila Abrami
    Daniele Riberio de Araujo
    Angélica F. A. Braga
    Michelle Georges Issa
    Humberto G. Ferraz
    Eneida de Paula
    Leonardo Fernandes Fraceto
    Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2007, 57 : 313 - 316
  • [23] Physicochemical characterization of zofenopril inclusion complex with 2-hydroxypropyl-β-cyclodextrin
    Udrescu, Lucretia
    Sbarcea, Laura
    Fulias, Adriana
    Ledeti, Ionut
    Vlase, Titus
    Barvinschi, Paul
    Kurunczi, Ludovic
    JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2015, 80 (04) : 485 - 497
  • [24] Characterization of the inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin
    Eid, Eltayeb E. M.
    Abdul, Ahmad Bustamam
    Suliman, Fakhr Eldin O.
    Sukari, Mohd A.
    Rasedee, A.
    Fatah, Safa S.
    CARBOHYDRATE POLYMERS, 2011, 83 (04) : 1707 - 1714
  • [25] Characterization of an inclusion complex of cholesterol and hydroxypropyl-β-cyclodextrin
    Williams, RO
    Mahaguna, V
    Sriwongjanya, M
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 1998, 46 (03) : 355 - 360
  • [26] Characterization of lidocaine:hydroxypropyl-β-cyclodextrin inclusion complex
    Moraes, Carolina Morales
    Abrami, Priscila
    de Araujo, Daniele Riberio
    Braga, Angelica F. A.
    Issa, Michelle Georges
    Ferraz, Humberto G.
    de Paula, Eneida
    Fraceto, Leonardo Fernandes
    JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 2007, 57 (1-4) : 313 - 316
  • [27] Ultrasound processed cuminaldehyde/2-hydroxypropyl-β-cyclodextrin inclusion complex: Preparation, characterization and antibacterial activity
    Cui, Haiying
    Siva, Subramanian
    Lin, Lin
    ULTRASONICS SONOCHEMISTRY, 2019, 56 : 84 - 93
  • [28] Preparation, Characterization, and Biotransformation of the Inclusion Complex of Phytosterols and Hydroxypropyl-β-cyclodextrin by Mycobacterium neoaurum
    Wang, Wenjun
    Yu, Longjiang
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES, 2011, 66 (5-6): : 277 - 282
  • [29] Preparation and thermal characterization of inclusion complex of Brazilian green propolis and hydroxypropyl-β-cyclodextrin
    Rocha, Bruno Alves
    Rodrigues, Marina Rezende
    Pires Bueno, Paula Carolina
    de Mello Costa-Machado, Ana Rita
    Lima Leite Vaz, Mirela Mara de Oliveira
    Nascimento, Andresa Piacezzi
    Barud, Hernane Silva
    Berretta-Silva, Andresa Aparecida
    JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2012, 108 (01) : 87 - 94
  • [30] Preparation, Characterization and in vitro Evaluation of Tosufloxacin Tosylate and Hydroxypropyl-β-cyclodextrin Inclusion Complex
    Hong, H. L.
    Sun, J. F.
    Zhang, Ying
    Zhu, Ning
    Han, L. M.
    Suo, Q. L.
    INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 81 (02) : 249 - 258
12345