Preparation and Characterization of Holmium-2-Hydroxypropyl β-Cyclodextrin Inclusion Complex and Its Stability under Gamma Radiation

被引：0
|
作者：
Lopez-Gonzalez, H. [1 ]
Jimenez-Becerril, J. [1 ]
Bautista-Santiago, C. [1 ]
Rojas-Hernandez, A. [2 ]
机构：
[1] Inst Nacl Invest Nucl, Dept Quim, Direcc Invest Cient, Gerencia Ciencias Bas, Mexico City 11801, Mexico
[2] Univ Autonoma Metropolitana Iztapalapa, Dept Quim, Area Quim Analit, Mexico City 09340, Mexico
来源：
RADIOCHEMISTRY | 2022年 / 64卷 / 06期
关键词：
holmium; 2-hydroxypropyl beta-cyclodextrin; inclusion complex; stability; gamma radiation; HOLMIUM NITRATE; 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN; NANOPARTICLES; GEL;
D O I：
10.1134/S1066362222060133
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The holmium inclusion complex with 2-hydroxypropyl beta-cyclodextrin (Ho-2-HP-beta-CD) was prepared and characterized by X-ray diffraction, IR and Raman spectroscopy, and thermogravimetric analysis. The preparation process involves the reaction of a solution of Ho(NO3)(3)center dot 5H(2)O with an aqueous solution of the 2-hydroxypropyl beta-cyclodextrin (2-HP-beta-CD). The compound's stability under gamma radiation in the range from 1 to 10000 Gy was studied. Only UV spectrophotometry reveals changes in the Ho-2-HP-beta-CD inclusion complex at the highest gamma radiation dose used. The stability at low doses and high solubility make Ho-2-HP-beta-CD inclusion complex a compound of interest in the new applications of lanthanides as therapeutic and biomedical agents.
引用
收藏
页码：757 / 765
页数：9
相关论文
共 50 条
  • [1] Preparation and Characterization of Holmium–2-Hydroxypropyl β-Cyclodextrin Inclusion Complex and Its Stability under Gamma Radiation
    H. López-González
    J. Jiménez-Becerril
    C. Bautista-Santiago
    A. Rojas-Hernández
    Radiochemistry, 2022, 64 : 757 - 765
  • [2] Preparation of Irisquinone Hydroxypropyl-β-Cyclodextrin Inclusion Complex and its thermodynamic stability
    Zhang, Xue-Nong
    Gong, Jin-Hong
    Tang, Li-Hua
    Zhang, Qiang
    2009 3RD INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING, VOLS 1-11, 2009, : 3219 - +
  • [3] Preparation and stability of the inclusion complex of astaxanthin with hydroxypropyl-β-cyclodextrin
    Yuan, Chao
    Jin, Zhengyu
    Xu, Xueming
    Zhuang, Haining
    Shen, Wangyang
    FOOD CHEMISTRY, 2008, 109 (02) : 264 - 268
  • [4] Preparation and characterization of the inclusion complex of hypocrellin A with hydroxypropyl-β-cyclodextrin
    Su, Yujie
    Rao, Shengqi
    Cai, Yujie
    Yang, Yanjun
    EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2010, 231 (05) : 781 - 788
  • [5] Preparation and characterization of the inclusion complex of hypocrellin A with hydroxypropyl-β-cyclodextrin
    Yujie Su
    Shengqi Rao
    Yujie Cai
    Yanjun Yang
    European Food Research and Technology, 2010, 231 : 781 - 788
  • [6] Preparation and characterization of the inclusion complex of furosemide with hydroxypropyl-β-cyclodextrin
    Vlachou, M
    Papaïoannou, G
    JOURNAL OF BIOMATERIALS APPLICATIONS, 2003, 17 (03) : 197 - 206
  • [7] Preparation and stability investigation of the inclusion complex of sulforaphane with hydroxypropyl-β-cyclodextrin
    Wu, Huahua
    Liang, Hao
    Yuan, Qipeng
    Wang, Tianxin
    Yan, Xu
    CARBOHYDRATE POLYMERS, 2010, 82 (03) : 613 - 617
  • [8] Preparation and characterization of cyanazine-hydroxypropyl-beta-cyclodextrin inclusion complex
    Gao, Shuang
    Bie, Chao
    Ji, Qiuyu
    Ling, Haiyang
    Li, Chunyan
    Fu, Ying
    Zhao, Lixia
    Ye, Fei
    RSC ADVANCES, 2019, 9 (45) : 26109 - 26115
  • [9] Preparation, characterization and antimicrobial activity of inclusion complex of biochanin A with (2-hydroxypropyl)-β-cyclodextrin
    Nikolic, Ivana Lj.
    Savic, Ivan M.
    Popsavin, Mirjana M.
    Rakic, Srdjan J.
    Mihajilov-Krstev, Tatjana M.
    Ristic, Ivan S.
    Eric, Suzana P.
    Savic-Gajic, Ivana M.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2018, 70 (11) : 1485 - 1493
  • [10] Preparation and characterization of spiro-acridine derivative and 2-hydroxypropyl-β-cyclodextrin inclusion complex
    Melo, Camila de Oliveira
    da Silva Rodrigues, Maria Salete
    Santos da Silva, Marcus Vinicius
    Marcelino, Henrique Rodrigues
    Rabello, Marcelo Montenegro
    de Moura, Ricardo Olimpio
    Oliveira, Elquio Eleamen
    JOURNAL OF MOLECULAR STRUCTURE, 2020, 1222 (1222)
12345