Proposal of a new and simple staging system of colorectal liver metastasis

被引:24
作者
Nagashima, Ikuo
Takada, Tadahiro
Nagawa, Hirokazu
Muto, Tetsuichiro
Okinaga, Kota
机构
[1] Teikyo Univ, Sch Med, Dept Surg, Itabashi Ku, Tokyo 1738605, Japan
[2] Univ Tokyo, Grad Sch Med, Dept Surg Oncol, Tokyo, Japan
关键词
colorectal liver metastasis; staging system; prognostic factor;
D O I
10.3748/wjg.v12.i43.6961
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
AIM: To create a new, simple and useful staging system for colorectal liver metastasis analogous to the Tumor Node Metastasis classification system of International Union Against Cancer. METHODS: A retrospective review was undertaken of 81 consecutive patients who underwent partial hepatectomy for colorectal liver metastases (group 1). Clinical and pathological features of both primary and metastatic liver cancers were entered into a multivariate analysis to determine independent variables helpful in accurately predicting long-term prognosis after hepatectomy. Using selected variables, we created a new staging system like TNM classification. The usefulness of the new staging system was examined in a series of 92 patients from another hospital (group 2). RESULTS: Multivariate analysis showed that 81 patients in group 1 had significant multiple hepatic tumors with the largest tumor being more than 5 cm in diameter, resectable extrahepatic distant metastases, and independent prognostic factors for poor survival after hepatectomy. Using these three variables, we created a new staging system to classify patients with colorectal liver metastases. Finally, our new staging system classified the patients both in group 1 and in group 2. CONCLUSION: Our new staging system of colorectal liver metastasis is simple and useful for staging patients. (c) 2006 The WJG Press. All rights reserved.
引用
收藏
页码:6961 / 6965
页数:5
相关论文
共 35 条
[31]   Pre-hepatectomy prognostic staging to determine treatment strategy for colorectal cancer metastases to the liver [J].
Tanaka, K ;
Shimada, H ;
Fujii, Y ;
Endo, I ;
Sekido, H ;
Togo, S ;
Ike, H .
LANGENBECKS ARCHIVES OF SURGERY, 2004, 389 (05) :371-379
[32]   Indicators for treatment strategies of colorectal liver metastases [J].
Ueno, H ;
Mochizuki, H ;
Hatsuse, K ;
Hase, K ;
Yamamoto, T .
ANNALS OF SURGERY, 2000, 231 (01) :59-66
[33]  
Yamada H, 2002, HEPATO-GASTROENTEROL, V49, P1265
[34]  
YAMAGUCHI A, 1993, INT SURG, V78, P16
[35]   THE INFLUENCE OF INTRAOPERATIVE HYPOTENSION AND PERIOPERATIVE BLOOD-TRANSFUSION ON DISEASE-FREE SURVIVAL IN PATIENTS WITH COMPLETE RESECTION OF COLORECTAL LIVER METASTASES [J].
YOUNES, RN ;
ROGATKO, A ;
BRENNAN, MF .
ANNALS OF SURGERY, 1991, 214 (02) :107-113