Predictions of index of hemolysis in shear blood flow (Effects of contact with wall and particle inertia)

This paper describes the effects of the particle inertia and the contact with the wall on hemolysis properties. The newly proposed methods of examining the inertia of red blood cells (particle) on particle path are discussed using computational fluid dynamics (CFD). In these methods, the particles are moved by Stokes drag including effects of difference of density between plasma and internal liquid in the blood. The results of computational analysis using these methods show that (1) the diameter of the particle (red blood cell), that is inertia of the cells, (2) the configuration of the objective wall boundary are important factors for this prediction. The results also show that if the inertia and the contact with the wall are considered, the precision of the prediction of the hemolysis properties will be improved comparing with that they are not considered.