Ultrastructural evidence of ependymal differentiation in a genetically proven atypical teratoid/rhabdoid tumor

被引：3

作者：

Antonelli, Manila ^{[1
]}

Cenacchi, Giovanna ^{[3
]}

Modena, Piergiorgio ^{[5
]}

Morra, Isabella ^{[4
]}

Forni, Marco ^{[4
]}

Giangaspero, Felice ^{[1
,2
]}

机构：

[1] Univ Roma La Sapienza, Dept Expt Med, Rome, Italy

[2] IRCCS Neuromed, Pozzilli, Isernia, Italy

[3] Univ Bologna, Sez Anat & Istol Patol, Dipartimento Clin Sci Radiol & Istocitopatol, Bologna, Italy

[4] Osped Infantile Regina Margherita, Dept Pathol, Turin, Italy

[5] Ist Nazl Tumori, Fdn IRCCS, Dept Expt Oncol, Mol Cytogenet Unit, I-20133 Milan, Italy

来源：

CHILDS NERVOUS SYSTEM | 2009年 / 25卷 / 12期

关键词：

Atypical teratoid/rhabdoid tumor; Ependymal differentiation; Multipotential differentiation; CENTRAL-NERVOUS-SYSTEM; RHABDOID TUMOR; CHILDHOOD; INFANCY;

D O I：

10.1007/s00381-009-0926-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We describe a case of genetically proven atypical teratoid/rhabdoid tumor (ATRT), showing ultrastructural evidence of ependymal differentiation. Such differentiation has not been reported so far in ATRT. This finding supports the concept that ATRTs as the majority of central nervous system embryonal tumors may derive from an immature and pluripotent neuroectodermal cell capable of differentiating along multiple lineages.

引用

页码：1627 / 1631

页数：5

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