Susceptibility of turkeys, chickens and chicken embryos to SARS-CoV-2

被引：12

作者：

Berhane, Yohannes ^{[1
,2
]}

Suderman, Matthew ^{[1
]}

Babiuk, Shawn ^{[1
,3
]}

Pickering, Bradley ^{[1
,4
,5
]}

机构：

[1] Canadian Food Inspect Agcy, Natl Ctr Foreign Anim Dis, Winnipeg, MB, Canada

[2] Univ Manitoba, Dept Anim Sci, Winnipeg, MB, Canada

[3] Univ Manitoba, Dept Immunol, Winnipeg, MB, Canada

[4] Univ Manitoba, Dept Med Microbiol & Infect Dis, Winnipeg, MB, Canada

[5] Iowa State Univ, Dept Vet Microbiol & Prevent Med, Coll Vet Med, Ames, IA USA

来源：

TRANSBOUNDARY AND EMERGING DISEASES | 2021年 / 68卷 / 06期

关键词：

chicken embryos; COVID-19; SARS-CoV-2; susceptibility; turkeys; chickens; CORONAVIRUSES; EPIDEMIOLOGY; PIGS;

D O I：

10.1111/tbed.13970

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The susceptibility of turkeys, chickens and chicken embryos to SARS-CoV-2 was evaluated by experimental infection. Turkeys and chickens were inoculated using a combination of intranasal, oral and ocular routes. Both turkeys and chickens did not develop clinical disease or seroconvert following inoculation. Viral RNA was not detected in oral swabs, cloacal swabs or in tissues using quantitative real-time RT-PCR. In addition, chicken embryos were inoculated by various routes including the yolk sac, intravenous, chorioallantoic membrane and allantoic cavity. In all instances, chicken embryos failed to support replication of the virus. SARS-CoV-2 does not affect turkeys or chickens in the current genetic state and does not pose any potential risk to establish an infection in both species of domestic poultry.

引用

页码：3038 / 3042

页数：5

共 20 条

[1] Susceptibility of Chicken Embryos, Sheep, Cattle, Pigs, and Chickens to Zika Virus Infection [J].

Ambagala, Aruna ;

Truong, Thang ;

Cottam-Birt, Colleen ;

Berhane, Yohannes ;

Gerdts, Volker ;

Karniychuk, Uladzimir ;

Safronetz, David ;

Babiuk, Shawn .

FRONTIERS IN VETERINARY SCIENCE, 2020, 7

[2] The proximal origin of SARS-CoV-2 [J].

Andersen, Kristian G. ;

Rambaut, Andrew ;

Lipkin, W. Ian ;

Holmes, Edward C. ;

Garry, Robert F. .

NATURE MEDICINE, 2020, 26 (04) :450-452

[3]

[Anonymous], 2020, WHO DIRECTOR GEN STA

[4]

[Anonymous], 2015, METHODS MOL BIOL, DOI [DOI 10.1007/978-1-4939-2438-7_1, 10.1007/978-1-4939-2438-71, 10.1007/978-1-4939-2438-7_1]

[5] SARS-CoV-2 does not replicate in embryonated hen's eggs or in MDCK cell lines [J].

Barr, Ian G. ;

Rynehart, Cleve ;

Whitney, Paul ;

Druce, Julian .

EUROSURVEILLANCE, 2020, 25 (25)

[6] Susceptibility of turkeys, chickens and chicken embryos to SARS-CoV-2 [J].

Berhane, Yohannes ;

Suderman, Matthew ;

Babiuk, Shawn ;

Pickering, Bradley .

TRANSBOUNDARY AND EMERGING DISEASES, 2021, 68 (06) :3038-3042

[7] Growth, detection, quantification, and inactivation of SARS-CoV-2 [J].

Case, James Brett ;

Bailey, Adam L. ;

Kim, Arthur S. ;

Chen, Rita E. ;

Diamond, Michael S. .

VIROLOGY, 2020, 548 :39-48

[8] Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR (Publication with Expression of Concern) [J].

Corman, Victor M. ;

Landt, Olfert ;

Kaiser, Marco ;

Molenkamp, Richard ;

Meijer, Adam ;

Chu, Daniel K. W. ;

Bleicker, Tobias ;

Bruenink, Sebastian ;

Schneider, Julia ;

Schmidt, Marie Luisa ;

Mulders, Daphne G. J. C. ;

Haagmans, Bart L. ;

van der Veer, Bas ;

van den Brink, Sharon ;

Wijsman, Lisa ;

Goderski, Gabriel ;

Romette, Jean-Louis ;

Ellis, Joanna ;

Zambon, Maria ;

Peiris, Malik ;

Goossens, Herman ;

Reusken, Chantal ;

Koopmans, Marion P. G. ;

Drosten, Christian .

EUROSURVEILLANCE, 2020, 25 (03) :23-30

[9] Epidemiology and Clinical Presentations of the Four Human Coronaviruses 229E, HKU1, NL63, and OC43 Detected over 3 Years Using a Novel Multiplex Real-Time PCR Method [J].

Gaunt, E. R. ;

Hardie, A. ;

Claas, E. C. J. ;

Simmonds, P. ;

Templeton, K. E. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2010, 48 (08) :2940-2947

[10]

Hu B., 2020, Nature, V579, P273, DOI DOI 10.1038/S41586-020-2012-7

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