Contributions of exopolysaccharides from lactic acid bacteria as biotechnological tools in food, pharmaceutical, and medical applications

被引：167

作者：

Daba, Ghoson M. ^{[1
]}

Elnahas, Marwa O. ^{[1
]}

Elkhateeb, Waill A. ^{[1
]}

机构：

[1] Natl Res Ctr, Chem Nat & Microbial Prod Dept, Pharmaceut Ind Res Div, El Buhouth St, Giza 12311, Egypt

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2021年 / 173卷

关键词：

Lactic acid bacteria; Biotechnology; Exopolysaccharides; Food; Pharmaceuticals; Applications;

D O I：

10.1016/j.ijbiomac.2021.01.110

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Exopolysaccharides (EPS) are important bioproducts produced by some genera of lactic acid bacteria. EPS are famous for their shelf-life improving properties, techno-functional enhancing abilities in food and dairy industries, besides their beneficial health effects. Furthermore, exopolysaccharides have many prospective and well-established contributions in the field of drugs and diagnostic industry. In this review, classification of EPS produced by LAB was presented. Moreover, current and potential applications of EPS in food, dairy, baking industries, cereal-based, and functional products were described. Also, some clinical and pharmaceutical applications of EPS such as intelligent drug delivery systems (microsystems and nanosystems for sustained delivery), interpenetrating polymer networks (IPNs), anticancer drug-targeting, recombinant macromolecular biopharmaceuticals, gene delivery, tissue engineering, and role of EPS in diagnostics were highlighted. Finally, future prospects concerning enhancing EPS production, minimizing costs of their production, and exploring their contribution in further applications were discussed. (C) 2021 Published by Elsevier B.V.

引用

页码：79 / 89

页数：11

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